2024
2023
2022
Youbin Kim, Hyejin Park, Youngwon Kim, Seo-Hyun Kim, Jae Hoon Lee, Hanseul Yang, Seo Jin Kim, Cathena Meiling Li, Haneul Lee, Do-Hyeong Na, Seowon Moon, Yumi Shin, Tae-In Kam, Han-Woong Lee, SangYun Kim, Ji-Joon Song, Yong-Keun Jung (2022). Pathogenic Role of RAGE in Tau Transmission and Memory Deficits. Biological Psychiatry, (), .
Ji-Eun Bae, Joon Bum Kim, Doo Sin Jo, Na Yeon Park, Yong Hwan Kim, Ha Jung Lee, Seong Hyun Kim, So Hyun Kim, Mikyung Son, Pansoo Kim, Hong-Yeoul Ryu, Won Ha Lee, Zae Young Ryoo, Hyun-Shik Lee, Yong-Keun Jung, Dong-Hyung Cho (2022). Carnitine Protects against MPP+-Induced Neurotoxicity and Inflammation by Promoting Primary Ciliogenesis in SH-SY5Y Cells. Cells, 11(17), 2722.
Jihoon Nah, Akihiro Shirakabe, Risa Mukai, Peiyong Zhai, Eun-Ah Sung, Andreas Ivessa, Wataru Mizushima, Yasuki Nakada, Toshiro Saito, Chengchen Hu, Yong-Keun Jung, Junichi Sadoshima (2022). Ulk1-dependent alternative mitophagy plays a protective role during pressure overload in the heart. Cardiovascular Research, (), .
2021
Jonghee Han, Junho Hyun, Jaesang Park, Sunmin Jung, Yoonseo Oh, Youbin Kim, Shin-Hyeon Ryu, Seo-Hyun Kim, Eun Il Jeong, Dong-Gyu Jo, Sung-Hye Park, Yong-Keun Jung (2021). Aberrant role of pyruvate kinase M2 in the regulation of gamma-secretase and memory deficits in Alzheimer's disease. Cell Reports, 37(10), .
Na Yeon Park, Doo Sin Jo, Yong Hwan Kim, Ji-Eun Bae, Joon Bum Kim, Hyun Jun Park, Ji Yeon Choi, Ha Jung Lee, Jeong Ho Chang, Heeyoun Bunch, Hong Bae Jeon, Yong-Keun Jung, Dong-Hyung Cho (2021). Triamterene induces autophagic degradation of lysosome by exacerbating lysosomal integrity. Archives of Pharmacal Research, 44(6), 621-631.
Daniel J Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, Mahmoud Abdellatif, Asghar Abdoli, Steffen Abel, Hagai Abeliovich, Marie H Abildgaard, Yakubu Princely Abudu, Abraham Acevedo-Arozena, Iannis E Adamopoulos, Khosrow Adeli, Timon E Adolph, Annagrazia Adornetto, Elma Aflaki, Galila Agam, Anupam Agarwal, Bharat B Aggarwal, Maria Agnello, Patrizia Agostinis, Javed N Agrewala, Alexander Agrotis, Patricia V Aguilar, S Tariq Ahmad, Zubair M Ahmed, Ulises Ahumada-Castro, Yong-Keun Jung, etc. (2021). Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy, 17(1), 1-382.
2020
Doo Sin Jo, So Jung Park, Ae-Kyeong Kim, Na Yeon Park, Joon Bum Kim, Ji-Eun Bae, Hyun Jun Park, Ji Hyun Shin, Jong Wook Chang, Peter K Kim, Yong-Keun Jung, Jae-Young Koh, Seong-Kyu Choe, Kyu-Sun Lee, Dong-Hyung Cho (2020). Loss of HSPA9 Induces Peroxisomal Degradation by Increasing Pexophagy. Autophagy, (), 1-15.
Juyong Kim, Siyoung Lee, Jaekyoon Kim, Sangwoo Ham, Jung Han Yoon Park, Seungbong Han, Yong-Keun Jung, Insop Shim, Jung-Soo Han, Ki Won Lee, Jiyoung Kim (2020). Ca2+-permeable TRPV1 Pain Receptor Knockout Rescues Memory Deficits and Reduces Amyloid-β and Tau in a Mouse Model of Alzheimer's Disease. Human Molecular Genetics, 29(2), 228-237.
2019
Ji Hyun Shin, So Jung Park, Doo Sin Jo, Na Yeon Park, Joon Bum Kim, Ji-Eun Bae, Yoon Kyung Jo, Jung Jin Hwang, Jin-A Lee, Dong-Gyu Jo, Jin Cheon Kim, Yong Keun Jung, Jae-Young Koh, Dong-Hyung Cho (2019). Down-regulated TMED10 in Alzheimer disease induces autophagy via ATG4B activation. Autophagy, 15(9), 1495-1505.
2018
2017
Hyeryeong Kim, Jee Young Sung, Eun-Kyung Park, Seongho Kho, Kyung Hee Koo, Seog-Yun Park, Sung-Ho Goh, Yoon Kyung Jeon, Sekyung Oh, Byung-Kiu Park, Yong-Keun Jung*, Yong-Nyun Kim* (2017). Regulation of anoikis resistance by NADPH oxidase 4 and epidermal growth factor receptor. British Journal of Cancer, 116(3), 370-381.
2016
Se-Hoon Hong*, Won Jae Lee*, Young Doo Kim, Hyunjoo Kim, Young-Jun Jeon, Bitna Lim, Dong-Hyung Cho, Won Do Heo, Doo-Hyun Yang, Chan-Young Kim, Han-Kwang Yang, Jin Kuk Yang, Yong-Keun Jung (2016). APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis. Oncotargets, 7(16), 21601-21617.
Sunmin Jung, Jihoon Nah, Jonghee Han, Seon-Guk Choi, Hyunjoo Kim, Jaesang Park, Ha-Kyung Pyo, Yong-Keun Jung (2016). Dual-specificity phosphatase 26 (DUSP26) stimulates Aβ42 generation by promoting Amyloid Precursor Protein axonal transport during hypoxia. Journal of Neurochemistry, 137(5), 770–781.
YoungDoo Kim*, Hyunwoo Choi*, WonJae Lee, Hyejin Park, Tae-In Kam, Se-Hoon Hong, Jihoon Nah, Sunmin Jung, Bora Shin, Huikyong Lee, Tae-Yong Choi, Hyosun Choo, Kyung-Keun Kim, Se-Young Choi, Rakez Kayed, Yong-Keun Jung (2016). Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model. Neurobiology of Disease, 87(), 19-28.
2015
2014
Jonghee Han, Sunmin Jung, Jiyeon Jang, Tae-In Kam, Hyunwoo Choi, Byung-Ju Kim, Jihoon Nah, Dong-Gyu Jo, Toshiyuki Nakagawa, Masaki Nishimura, Yong-Keun Jung (2014). OCIAD2 activates γ-secretase to enhance amyloid β production by interacting with nicastrin. Cellular and Molecular Life Sciences, 71(13), 2561-2576.
Hyunjoo Kim, Ho-June Lee, Yumin Oh, Seon-Guk Choi, Se-Hoon Hong, Hyo-Jin Kim, Song-Yi Lee, Ji-Woo Choi, Deog Su Hwang, Key-Sun Kim, Hyo-Joon Kim, Jianke Zhang, Hyun-Jo Youn, Dong-Young Noh, Yong-Keun Jung (2014). The DUSP26 phosphatase activator adenylate kinase 2 regulates FADD phosphorylation and cell growth. Nature Communnications, 5(), 3351.
Wonchull Kang, Se Hoon Hong, Hye Min Lee, Na Yeon Kim, Yun Chan Lim, Le Thi My Le, Bitna Lim, Hyun Chul Kim, Tae Yeon Kim, Hiroki Ashida, Akiho Yokota, Sang Soo Hah, Keun Ho Chun, Yong-Keun Jung, Jin Kuk Yang (2014). Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme. PNAS, 111(1), 54-61.
2013
Jong-Sung Park, Silvia Manzanero, Jae-Woong Chang, Yuri Choi, Sang-Ha Baik, Yi-Lin Cheng, Yu-I Li, A-Ryeong Gwon, Ha-Na Woo, Jiyeon Jang, In-Young Choi, Joo-Yong Lee, Yong-Keun Jung, Sung-Chun Tang, Christopher G Sobey, Thiruma V Arumugam, Dong-Gyu Jo (2013). Calsenilin contributes to neuronal cell death in ischemic stroke. Brain Pathology, 23(4), 402-412.
Tae-In Kam, Sungmin Song, Youngdae Gwon, Hyejin Park, Ji-Jing Yan, Isak Im, Ji-Woo Choi, Tae-Yong Choi, Jeongyeon Kim, Dong-Keun Song, Toshiyuki Takai, Yong-Chul Kim, Key-Sun Kim, Se-Young Choi, Sukwoo Choi, William L Klein, Junying Yuan, Yong-Keun Jung (2013). FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer's disease. The Journal of Clinical Investigation, 123(7), 2791-2802.
2012
Huikyong Lee, Jee-Yeon Noh, Yumin Oh, Youngdoo Kim, Jae-Woong Chang, Chul-Woong Chung, Soon-Tae Lee, Manho Kim, Hoon Ryu, Yong-Keun Jung (2012). IRE1 plays an essential role in ER stress-mediated aggregation of mutant huntingtin via the inhibition of autophagy flux. Human Molecular Genetics, 21(1), 101-114.
2011
2010
Hye-Eun Han, Saravanan Sellamuthu, Bae Hyun Shin, Yong Jae Lee, Sungmin Song, Ji-Seon Seo, In-Sun Baek, Jeomil Bae, Hannah Kim, Yung Joon Yoo, Yong-Keun Jung, Woo Keun Song, Pyung-Lim Han, Woo Jin Park (2010). The nuclear inclusion a (NIa) protease of turnip mosaic virus (TuMV) cleaves amyloid-β. PLoS One, 5(12), e15645.
Sunggeon Ko, Gil Bu Kang, Sung Min Song, Jung-Gyu Lee, Dong Yeon Shin, Ji-Hye Yun, Yi Sheng, Chaejoon Cheong, Young Ho Jeon, Yong-Keun Jung, Cheryl H Arrowsmith, George V Avvakumov, Sirano Dhe-Paganon, Yung Joon Yoo, Soo Hyun Eom, Weontae Lee (2010). Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity. Journal of Biological Chemistry, 285(46), 36070-36080.
Cheol-Hee Choi, Yong-Keun Jung, Seon-Hee Oh (2010). Autophagy induction by capsaicin in malignant human breast cells is modulated by p38 and extracellular signal-regulated mitogen-activated protein kinases and retards cell death by suppressing endoplasmic reticulum stress-mediated apoptosis. Molecular Pharmacology, 78(1), 114-125.
2009
Hyo-Jin Kim, Ho-June Lee, Joon-Il Jun, Yumin Oh, Seon-Guk Choi, Hyunjoo Kim, Chul-Woong Chung, In-Ki Kim, Il-Sun Park, Han-Jung Chae, Hyung-Ryong Kim, Yong-Keun Jung (2009). Intracellular cleavage of osteopontin by caspase-8 modulates hypoxia/reoxygenation cell death through p53. PNAS, 106(36), 15326-15331.
Yoshihiro Suzuki, Kazunori Ohta, Masanori Itoh, Yukari Sakoh-Sumitomo, Teruhiko Mitsuda, Masashi Ueda, Yoshika Hayakawa-Yano, Shimo Li, Yoko Hida, Takashi Inuzuka, Yong-Keun Jung, Toshiyuki Nakagawa (2009). An alternative spliced mouse presenilin-2 mRNA encodes a novel gamma-secretase inhibitor. FEBS Letters, 583(9), 1403-1408.
Jee-Yeon Noh, Huikyong Lee, Sungmin Song, Nam Soon Kim, Wooseok Im, Manho Kim, Hyemyung Seo, Chul-Woong Chung, Jae-Woong Chang, Robert J Ferrante, Young-Jun Yoo, Hoon Ryu, Yong-Keun Jung (2009). SCAMP5 links endoplasmic reticulum stress to the accumulation of expanded polyglutamine protein aggregates via endocytosis inhibition. Journal of Biological Chemistry, 284(17), 11318-11325.
2008
Jong-Ok Pyo, Jihoon Nah, Hyo-Jin Kim, Jae-Woong Chang, Young-Wha Song, Dong-Kwon Yang, Dong-Gyu Jo, Hyung-Ryong Kim, Han-Jung Chae, Soo-Wan Chae, Seung-Yong Hwang, Seung-Jun Kim, Hyo-Joon Kim, Chunghee Cho, Chang-Gyu Oh, Woo Jin Park, Yong-Keun Jung (2008). Protection of cardiomyocytes from ischemic/hypoxic cell death via Drbp1 and pMe2GlyDH in cardio-specific ARC transgenic mice. Journal of Biological Chemistry, 283(45), 30707-30714.
Sungmin Song, Huikyong Lee, Tae-In Kam, Mei Ling Tai, Joo-Yong Lee, Jee-Yeon Noh, Sang Mi Shim, Soo Jung Seo, Young-Yun Kong, Toshiyuki Nakagawa, Chul-Woong Chung, Deog-Young Choi, Hammou Oubrahim, Yong-Keun Jung (2008). E2-25K/Hip-2 regulates caspase-12 in ER stress-mediated Abeta neurotoxicity. Journal of Cell Biology, 182(4), 675-684.
2007
Ho-June Lee, Jong-Ok Pyo, Yumin Oh, Hyo-Jin Kim, Se-hoon Hong, Young-Jun Jeon, Hyunjoo Kim, Dong-Hyung Cho, Ha-Na Woo, Sungmin Song, Jung-Hyun Nam, Hyo Joon Kim, Key-Sun Kim, Yong-Keun Jung (2007). AK2 activates a novel apoptotic pathway through formation of a complex with FADD and caspase-10. Nature Cell Biology, 9(11), 1303-1310.
Do-Sung Kim, Eun-Rhan Woo, Soo-Wan Chae, Ki-Chan Ha, Geum-Hwa Lee, Seong-Tshool Hong, Dae-Young Kwon, Myung-Sunny Kim, Yong-Keun Jung, Hyung-Min Kim, Hye-Kyung Kim, Hyung-Ryong Kim, Han-Jung Chae (2007). Plantainoside D protects adriamycin-induced apoptosis in H9c2 cardiac muscle cells via the inhibition of ROS generation and NF-kappaB activation. Life Sciences, 80(4), 314-323.
2006
2005
Sungeun Hong, Inchul Choi, Jong-Min Woo, Jungsu Oh, Taewan Kim, Eunyoung Choi, Tae-Wan Kim, Yong-Keun Jung, Do Han Kim, Choong-Hyun Sun, Gwan-Su Yi, Edward M Eddy, Chunghee Cho (2005). Identification and integrative analysis of 28 novel genes specifically expressed and developmentally regulated in murine spermatogenic cells. Journal of Biological Chemistry, 280(9), 7685-7693.
Jong-Ok Pyo, Mi-Hee Jang, Yun-Kyung Kwon, Ho-June Lee, Joon-Il Jun, Ha-Na Woo, Dong-Hyung Cho, Boyoun Choi, Heuiran Lee, Joo-Hang Kim, Noboru Mizushima, Yoshinori Oshumi, Yong-Keun Jung (2005). Essential roles of Atg5 and FADD in autophagic cell death: dissection of autophagic cell death into vacuole formation and cell death. Journal of Biological Chemistry, 280(21), 20722-20729.
2004
Ha-Na Woo, Gil-Sun Hong, Joon-Il Jun, Dong-Hyung Cho, Hyun-Woo Choi, Ho-June Lee, Chul-Woong Chung, In-Ki Kim, Dong-Gyu Jo, Jong-Ok Pyo, John Bertin, Yong-Keun Jung (2004). Inhibition of Bcl10-mediated activation of NF-kappa B by BinCARD, a Bcl10-interacting CARD protein. FEBS Letters, 578(3), 239-244.