안광석

안광석

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안광석

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안광석 Ahn, Kwangseog

안광석
연구분야
면역학 바이러스학 세포생물학

1.   HCMV virology: Mechanism of Latency-Reactivation
· HCMV nuclear entry and Latency establishment 

· Discover the role of viral long non-coding RNAs in HCMV latency-reactivation

· Epitranscriptomic features of HCMV latency-reactivation

· Investigate therapeutic targets of HCMV latent-infected cells

 

2.   Retroelements in Host-Virus interaction 
· Interaction between L1 retrotransposon and HCMV 

· Landscape of HIV-1 latent infection integration sites
· RNA biology of Hepatitis B virus 

 

 

학력/경력/수상내역
학력
  • - 1994 Ph.D. : University of Illinois at Urbana-Champaign
  • - 1987 M.S. : Seoul National University
  • - 1985 B.S. : Seoul National University
  • - 1981 청주고등학교
경력
  • - 2006 - 2015 Director, National Creative Research Initiatives Center for Antigen Presentation
  • - 2004 - Present Professor, Seoul National University, Department of Biological Sciences
  • - 2002 - 2003 Visiting Professor, Oregon Health & Science University
  • - 1997 - 2004 Associate professor, Korea University
  • - 1996 - 1997 Scientist, Johnson & Johnson
  • - 1994 - 1996 Post-Doc, The Scripps Research Institute (San Diego), Dept. of Immunology)
주요논문
  1. Hong, Y., Jeong, H., Park, K., Lee, S., Shim, J., Kim, Song, Y., Park, S., Park, H., Kim, NV. & Ahn. K. (2021). STING Facilitates Nuclear Import of Herpesvirus Genome During Infection. Proc Natl Acad Sci USA. 118 (33) e2108631118.
  2. Hwang, S., Jung, H., Mun, S., Lee. S., et al. & Ahn, K. (2021). L1 retrotransposons exploit RNA m6A modification as an evolutionary driving force. Nature Communications 12:880.
  3. Song, J., Lee, S., Cho, D.Y., Lee, S., Kim, H., Yu, N., Lee, S., and Ahn, K. (2019). Human cytomegalovirus induces and exploits Roquin to counteract the IRF1-mediated antiviral state. Proc Natl Acad Sci USA 116, 18619-18628.
  4. Kim, S., Seo, D., Kim, D., Hong, Y., Chan, H., Baek, D., Kim, VN., Lee., S., and Ahn, K. Temporal landscape of micrRNA-mediated host-virus crosstalk during productive human cytomegalovirus infection. Cell Host & Microbe 17:838-851 (2015). Highlighted as "Featured Article".
  5. Ryoo, J., Choi, J., Oh, C., Kim, S., Seo, M., Kim, S-Y., Seo, D., Kim, J., White, TE., Brandariz-Nunez, A., Diaz-Griferero, A., Yun, C-H., Hollenbaugh, JA., Kim, B., Baek., D., and Ahn, K. The ribonuclease activity of SAMHD1 is required for HIV-1 restriction. Nature Medicine 20:936-941 (2014). Highlighted in NEWS AND VIEWS of the issue (p.808-809).
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