조교수
이홍균 Lee, Hong-Gyun
연구분야
면역학
신경생물학
Our research focuses on understanding how glial immunity controls health and disease in the central nervous system (CNS) and the enteric nervous system (ENS). Using advanced technologies, we investigate the dynamic interactions between glial cells and immune cells to understand inflammation and tissue homeostasis, aiming to develop novel therapeutic approaches for neurological and gastrointestinal disease.
학력/경력
학력
- - 2013.03 ~ 2020.02 박사: 한양대학교, 생명과학과
- - 2009.03 ~ 2013.02 학사: 한양대학교, 생명과학과
경력
- - 2025.03 ~ 현재 조교수, 서울대학교 생명과학부
- - 2021.03 ~ 2025. 01 박사후연구원, Harvard Medical School | Brigham and Women’s Hospital
- - 2020.03 ~ 2021. 02 박사후연구원, 한양대학교
주요논문
- Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. “Disease-Associated Astrocyte Epigenetic Memory Promotes CNS Pathology” Nature, 2024 Mar;627(8005):865-872.
- Lee HG*, Lee JH*, Flausino LE*, Quintana FJ. “Neuroinflammation: An Astrocyte Perspective” Sci Transl Med, 2023 Nov 8;15(721):eadi7828. (*denotes co-first author)
- Wheeler MA*, Clark IC*, Lee HG*, Li Z, Linnerbauer M, Rone JM, Blain M, Akl CF, Piester G, Giovannoni F, Charabati M, Lee JH, Kye YC, Choi J, Sanmarco LM, Srun L, Chung EN, Flausino LE, Andersen BM, Rothhammer V, Yano H, Illouz T, Zandee SEJ, Daniel C, Artis D, Prinz M, Abate AR, Kuchroo VK, Antel JP, Prat A, Quintana FJ. “Droplet-Based Forward Genetic Screening of Astrocyte-Microglia Cross-Talk” Science, 2023 Mar 10;379(6636):1023-1030. (*denotes co-first author)
- Lee HG*, Wheeler MA*, Quintana FJ. “Function and Therapeutic Value of Astrocytes in Neurologic Diseases” Nat Rev Drug Discov, 2022 May;21(5):339-358. (*denotes co-first author)
- Lee HG, Lee JU, Kim DH, Lim S, Kang IS, Choi JM. “Pathogenic Function of Bystander-activated Memory-like CD4+ T cells in Autoimmune Encephalomyelitis” Nat Commun, 2019 Feb 12;10(1):709.