Seoul National University Biological Sciences Website

논문

Laboratory of Biochemistry and Cell Biology

Biochem Biophys Res Commun.

Jung I, Sohn DH, Choi J, Kim JM, Jeon S, Seol JH, Seong RH. (2012). SRG3/mBAF155 stabilizes the SWI/SNF-like BAF complex by blocking CHFR mediated ubiquitination and degradation of its major components.. Biochem Biophys Res Commun., 418(3), 512.

Biochemical and Biophysical Research Communications

Bae SJ, Kwon YE, Kim M*, Seol JH* (2013). CHFR is negatively regulated by SUMOylation-mediated ubiquitylation. Biochemical and Biophysical Research Communications, 433(2), 194.

Kwon YE, Bae SJ, Kim M*, Seol JH* (2013). SUMOylation negatively regulates the stability of CHFR tumor suppressor. Biochemical and Biophysical Research Communications, 430(1), 213.

Kim, J. M., Cho, E. N., Kwon, Y. E., Bae, S. J., Kim, M.*, Seol, J. H.* (2010). CHFR functions as a ubiquitin ligase for HLTF to regulate its stability and functions. Biochemical and Biophysical Research Communications, 395(4), 515-520.

Song, K. S., Kim, K., Chung, K. C., Seol, J. H., Yoon, J. H. (2008). Interaction of SOCS3 with NonO attenuates IL-1beta-dependent MUC8 gene expression.. Biochemical and Biophysical Research Communications, 377(3), 946-951.

Oh, Y. M., Yoo, S. J., Seol, J. H. (2007). Deubiquitination of Chfr, a checkpoint protein, by USP7/HAUSP regulates its stability and activity. Biochemical and Biophysical Research Communications, 357(3), 615-619.

Kang, S. A., Seol, J. H., Kim, J. (2005). The conserved WRPW motif of Hes6 mediates proteasomal degradation. Biochemical and Biophysical Research Communications, 332(1), 33-36.

Oh, J. Y., Eun, Y. M., Yoo, S. J., Seol, J. H., Seong, I. S., Lee, C. S., and Chung, C. H. (1998). LonR9 carrying a single Glu614 to Lys mutation inhibits the ATP-dependent protease La (Lon) by forming mixed oligomeric complexe. Biochemical and Biophysical Research Communications, 250(1), 32-35.

Chung, C. H., Yoo, S. J., and Seol, J. H. (1997). Characterization of energy-dependent proteases in bacteria. Biochemical and Biophysical Research Communications, 241(4), 613-616.

Yoo, S. J. Seol, J. H., Seong, I. S., Kang, M. S., and Chung, C. H. (1997). ATP binding, but not its hydrolysis, is required for assembly and proteolytic activity of the HslVU protease in Escherichia coli. Biochemical and Biophysical Research Communications, 238(2), 581-585.

Yoo, S. J., Seol, J. H., Kang, M. S., and Chung, C. H. (1996). Poly-L-lysine activates both peptide and ATP hydrolysis by the ATP-dependent HslVU protease in Escherichia coli. Biochemical and Biophysical Research Communications, 229(2), 531-535.

Seol, J. H., Woo, K. M., Kang, M. S., Ha, D. B., and Chung, C. H. (1995). Requirement of ATP-hydrolysis for ClpA/ClpP complex, the ATP-dependent protease Ti in Escherichia coli. Biochemical and Biophysical Research Communications, 217(1), 41-51.

Yoo, S. J., Seol, J. H., Kang, M. S., Ha, D. B., and Chung, C. H. (1994). clpX encoding an alternative ATP-binding subunit of protease Ti (Clp) can be expressed independently from clpP in Escherichia coli. Biochemical and Biophysical Research Communications, 203(2), 798-804.

Seol, J. H., Woo, S. K., Jung, E. M., Yoo, S. J., Lee, C. S., Kim, K., Tanaka, K., Ichihara, A., Ha, D. B., and Chung, C. H. (1991). Protease Do is essential for survival of Escherichia coli at high temperatures: its identity with the htrA gene product. Biochemical and Biophysical Research Communications, 176(2), 730-736.

Biological Chemistry

Seol, J. H., Kwon, J. A., Kang, M. S., and Chung, C. H. (1997). Site-directed mutagenesis of the Cys residues in ClpA, the ATPase component of protease Ti (ClpAP) in Escherichia coli. Biological Chemistry, 378(10), 1205-1209.

Chung, C. H., Seol, J. H., and Kang, M. S. (1996). Protease Ti (Clp), a multi-component ATP-dependent protease in Escherichia coli.. Biological Chemistry, 377(9), 549-554.

Cancer Research

Joo JH, Oh H, Kim M, An EJ, Kim RK, Lee SY, Kang DH, Kang SW, Park CK, Kim H, Lee SJ, Lee D*, Seol JH*, Bae YS*. (2016). NADPH oxidase 1 activity and ROS generation are regulated by Grb2/Cbl-mediated proteasomal degradation of NoxO1 in colon cancer cells.. Cancer Research, (), .

Cell

Shou, W., Seol, J. H., Shevchenko, A., Baskerville, C., Moazed, D., Chen, Z. W., Jang, J., Shevchenko, A., Charbonneau, H., and Deshaies, R. J. (1999). Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex. Cell, 97(2), 233-244.

Cell Death Differ.

Oh KH, Yang SW, Park JM, Seol JH, Iemura S, Natsume T, Murata S, Tanaka K, Jeon YJ, Chung CH. (2011). Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme.. Cell Death Differ., 18(8), 1326-36.

Cell host and microbe

Lee K, Cho KC, Kim BR, Jang IH, Nam KB, Kwon YE, Kim M, Hyeon DY, Hwang DH, Seol JH, Lee WJ (2018). Inflammation-Modulated Metabolic Reprogramming Is Required for DUOX-Dependent Gut Immunity in Drosophila. Cell host and microbe, 23(3), 338-352.

Diabetes

Koo YD, Choi JW, Kim M, Chae S, Ahn BY, Kim M, Oh BC, Hwang D, Seol JH, Kim YB, Park YJ, Chung SS, Park KS. (2015). SUMO-specific protease 2 (SENP2) is an important regulator of fatty acid metabolism in skeletal muscle.. Diabetes, 64(7), 2420.

European Journal of Biochemistry

Seol, J. H., Yoo, S. J., Shin, D. H., Shim, Y. K., Kang, M. S., Goldberg, A. L., and Chung, C. H. (1997). The heat-shock protein HslVU from Escherichia coli is a protein-activated ATPase as well as an ATP-dependent proteinase. European Journal of Biochemistry, 247(3), 1143-1150.

FEBS Letters

Seong, I. S., Oh, J. Y., Yoo, S. J., Seol, J. H., and Chung, C. H. (1999). ATP-dependent degradation of SulA, a cell division inhibitor, by the HslVU protease in Escherichia coli.. FEBS Letters, 456(1), 211-214.

Yoo, S. J., Shim, Y. K., Seong, I. S., Seol, J. H., Kang, M. S., and Chung, C. H. (1997). Mutagenesis of two N-terminal Thr and five Ser residues in HslV, the proteolytic component of the ATP-dependent HslVU protease. FEBS Letters, 412(1), 57-60.

Shin, D. H., Yoo, S. J., Shim, Y. K., Seol, J. H., Kang, M. S., and Chung, C. H. (1996). Mutational analysis of the ATP-binding site in HslU, the ATPase component of HslVU protease in Escherichia coli. FEBS Letters, 398(2-3), 151-154.

Yoo, S. J., Seol, J. H., Woo, S. K., Suh, S. W., Hwang, D. S., Ha, D. B., and Chung, C. H. (1993). Hydrolysis of IciA protein, an inhibitor of DNA replication initiation, by protease Do in Escherichia coli. FEBS Letters, 327(1), 17-20.

Lee, H. R., Seol, J. H., Kim, O. M., Lee, C. S., Suh, S. W., Hong, Y. M., Tanaka, K., Ichihara, A., Ha, D. B., and Chung, C. H. (1991). Molecular cloning of the Ecotin gene in Escherichia coli. FEBS Letters, 287(1-2), 53-56.

Seol, J. H., Park, S. C., Ha, D. B., Tanaka, K., Ichihara, A., and Chung, C. H. (1989). Na+, K+-specific inhibition of protein and peptide hydrolyses by proteasome from human hepatoma tissues. FEBS Letters, 247(2), 197-200.

Genes & Development

Seol, J. H., Feldman, R. M. R., Zachariae, W., Shevchenko, A., Correll, C. C., Lyapina, S., Chi, Y., Galova, M., Claypool, J., Sandmeyer, S., Nasmyth, K., Shevchenko, A., and Deshaies, R. J. (1999). Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes & Development, 13(12), 1614-1626.

J Clin Invest.

Jeon YJ, Jo MG, Yoo HM, Hong SH, Park JM, Ka SH, Oh KH, Seol JH, Jung YK, Chung CH. (2012). Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15.. J Clin Invest., 122(7), 2622-36.

J Mol Biol. 2013

Park E, Lee JW, Yoo HM, Ha BH, An JY, Jeon YJ, Seol JH, Eom SH, Chung CH. (2013). Structural Alteration in the Pore Motif of the Bacterial 20S Proteasome Homolog HslV Leads to Uncontrolled Protein Degradation.. J Mol Biol. 2013, (), .

Mol Cell.

Park JM, Yang SW, Yu KR, Ka SH, Lee SW, Seol JH, Jeon YJ, Chung CH. (2014). Modification of PCNA by ISG15 Plays a Crucial Role in Termination of Error-Prone Translesion DNA Synthesis.. Mol Cell., 54(4), 626-638.

Mol Cells

Kim M, Chen Z, Shim MS, Lee MS, Kim JE, Kwon YE, Yoo TJ, Kim JY, Bang JY, Carlson BA, Seol JH, Hatfield DL, Lee BJ. (2013). SUMO modification of NZFP mediates transcriptional repression through TBP binding.. Mol Cells, 35(1), 70-8.

Molecular & Cellular Proteomics

Graumann, J., Dunipace, L. A., Seol, J.H., McDonald, H. W., Yates, J. R., Wold, B. J., and Deshaies, R. J. (2004). Applicability of tandem affinity purification MudPIT to pathway proteimics in yeast. Molecular & Cellular Proteomics, 3(3), 226-237.

Deshaies, R. J., Seol, J. H., McDonald, H. W., Cope, G., Lyapina, S., Shevchenko, A., Shevchenko, A., Verma, R., and Yates, J. (2002). Charting the protein complexome in yeast by mass spectrometry. Molecular & Cellular Proteomics, 1(1), 3-10.

Molecular and Cellular Biology

Galan, J-M., Wiederkehr, A., Seol, J. H., Deshaies, R. J., Riezman, H., and Peter, M. (2001). Skp1p and the F-box protein Rcy1p form a non-SCF complex involved in recycling of the SNARE Snc1p in yeast. Molecular and Cellular Biology, 21(9), 3105-3117.

Molecular Biology of the Cell

Jeon, Y. J., Choi, J. S., Lee, J. Y., Yu, K. R., Ka, S. H., Cho, Y., Choi, E. J., Baek, S. H., Seol, J. H., Park, D., Bang, O. S., Chung, C. H. (2008). Filamin B serves as a molecular scaffold for type I interferon-induced c-Jun NH2-terminal kinase signaling pathway. Molecular Biology of the Cell, 19(12), 5116-5130.

Molecules and Cells

Kwon, Y. E., Kim, Y. S., Oh, Y. M., Seol, J. H. (2009). Nuclear localization of Chfr is crucial for its checkpoint function. Molecules and Cells, 27(3), 359-363.

Lee, J. W., Park, E., Bang, O., Eom, S. H., Cheong, G. W., Chung, C. H., Seol, J. H. (2007). Nucleotide triphosphates inhibit the degradation of unfolded proteins by HslV peptidase. Molecules and Cells, 23(2), 252-257.

Nat Commun.

Park JH, Yang SW, Park JM, Ka SH, Kim JH, Kong YY, Jeon YJ, Seol JH*, Chung CH*. (2016). Positive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification.. Nat Commun., 7(), 12513.

Nature

Clark, I. E., Dodson, M. W., Jiang, C., Cao, J. H., Huh, J. R., Seol, J. H., Yoo, S. J., Hay, B. A., Guo, M. (2006). Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature, 441(7097), 1162-1166.

Nature Cell Biology

Oh, Y. M., Kwon, Y. E., Kim, J. M., Bae, S. J., Lee, B. K., Yoo, S. J., Chung, C. H., Deshaies, R. J., Seol, J. H. (2009). Chfr is linked to tumour metastasis through the downregulation of HDAC1. Nature Cell Biology, 11(3), 295-302.

Lee, M. H., Lee, S. W., Lee, E. J., Choi, S. J., Chung, S. S., Lee, J. I., Cho, J. M., Seol, J. H., Baek, S. H., Kim, K. I., Chiba, T., Tanaka, K., Bang, O. S., Chung, C. H. (2006). SUMO-specific protease SUSP4 positively regulates p53 by promoting Mdm2 self-ubiquitination. Nature Cell Biology, 8(12), 1424-1431.

Seol, J. H., Shevchenko, A., Shevchenko, A., and Deshaies, R. J. (2001). Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nature Cell Biology, 3(4), 384-391.

NATURE COMMUNICATIONS

Bae SJ^, Kim M^, Kim SH, Kwon YE, Lee JH, Kim J, Chung CH, Lee WJ*, Seol JH*. (2015). NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo signalling pathway. NATURE COMMUNICATIONS, 6(), 6314.

Neoplasia

Seong MW, Ka SH, Park JH, Park JH, Yoo HM, Yang SW, Park JM, Park D, Lee ST, Seol JH*, Chung CH* (2015). Deleterious c-Cbl Exon Skipping Contributes to Human Glioma. Neoplasia, 17(6), 518-524.

PLoS ONE

Jeong, J. H., Song, H. R., Ko, J. H., Jeong, Y. M., Kwon, Y. E., Seol, J. H., Amasino, R. M., Noh, B., Noh, Y. S. (2009). Repression of FLOWERING LOCUS T chromatin by functionally redundant histone H3 lysine 4 demethylases in Arabidopsis. PLoS ONE, 4(11), e8033.

Proceedings of the National Academy of Sciences

Rohrwild, M., Coux, O., Huang, H. C., Moerschell, R. P., Yoo, S. J., Seol, J. H., Chung, C. H., and Goldberg, A. L. (1996). HslV-HslU: a novel ATP-dependent protease complex in Escherichia coli related to the eukaryotic proteasome. Proceedings of the National Academy of Sciences, 93(12), 5808-5813.

Rapid Commun Mass Spectrom.

Jung JW, Bae SJ, Kang GY, Kim KH, Yeo WS, Park SH, Seol JH, Yi EC, Kim KP. (2013). Analysis of the biochemical role of Lys-11 in polyubiquitin chain formation using quantitative mass spectrometry.. Rapid Commun Mass Spectrom., 27(2), 339-46.

Scientific Reports

Kim M, Kwon YE, Song JO, Bae SJ, Seol JH (2016). CHFR negatively regulates SIRT1 activity upon oxidative stress.. Scientific Reports, 6(), 37578.

The EMBO Journal

Ryu, J. H., Ha, E. M., Oh, C. T., Seol, J. H., Brey, P. T., Jin, I., Lee, D. G., Kim, J., Lee, D., Lee, W. J. (2006). An essential complementary role of NF-kappaB pathway to microbicidal oxidants in Drosophila gut immunity. The EMBO Journal, 25(15), 3693-3701.

Kang, M. S., Lim, B. K., Seong, I. S., Seol, J. H., Tanahashi, N., Tanaka, K., and Chung, C. H. (2001). The ATP-dependent CodWX (HslVU) protease in Bacillus subtilis is an N-terminal serine protease. The EMBO Journal, 20(4), 734-742.

The Journal of Biological Chemistry

Lee, J. W., Park, E., Jeong, M. S., Jeon, Y. J., Eom, S. H., Seol, J. H., Chung, C. H. (2009). HslVU ATP-dependent protease utilizes maximally six among twelve threonine active sites during proteolysis. The Journal of Biological Chemistry, 284(48), 33475-33484.

Park, E., Lee, J. W., Eom, S. H., Seol, J. H., Chung, C. H. (2008). Binding of MG132 or deletion of the Thr active sites in HslV subunits increases the affinity of HslV protease for HslU ATPase and makes this interaction nucleotide-independent. The Journal of Biological Chemistry, 283(48), 33258-33266.

Kang, S. H., Kim, G. R., Seong, M., Baek, S. H., Seol, J. H., Bang, O. S., Ovaa, H. , Tatsumi, K. , Komatsu, M., Tanaka, K., Chung, C. H. (2007). Two novel ubiquitin-fold modifier 1 (Ufm1)-specific Proteases, UfSP1 and UfSP2. The Journal of Biological Chemistry, 282(8), 5256-5262.

Huh, J. R., Foe, I., Muro, I., Chen, C. H., Seol, J. H., Yoo, S. J., Guo, M., Park, J. M., Hay, B. A. (2007). The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis induce. The Journal of Biological Chemistry, 282(3), 2056-2068.

Choi, S. J., Chung, S. S., Rho, E. J., Lee, H. W., Lee, M. H., Choi, H. S., Seol, J. H., Baek, S. H., Bang, O. S., Chung, C. H. (2006). Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1. The Journal of Biological Chemistry, 281(41), 30669-30677.

Kwon, J. E., La, M., Oh, K. H., Oh, Y. M., Kim, G. R., Seol, J. H., Baek, S. H., Chiba, T., Tanaka, K., Bang, O. S., Joe, C. O., Chung, C. H. (2006). BTB domain-containing speckle-type POZ protein (SPOP) serves as an adaptor of DAXX for ubiquitination by Cul3-based ubiquitin ligase.. The Journal of Biological Chemistry, 281(18), 12664-12672.

Park, E., Rho, Y. M., Koh, O. J., Ahn, S. W., Seong, I. S., Song, J. J., Bang, O., Seol, J. H., Wang, J., Eom, S. H., Chung, C. H. (2005). Role of the GYVG pore motif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase.. The Journal of Biological Chemistry, 280(24), 22892-22898.

Yoo, S. J., Kim, H. H., Shin, D. H., Lee, C. S., Seong, I. S., Seol, J. H., Shimbara, N., Tanaka, K., and Chung, C. H. (1998). Effects of the Cys Mutations on Structure and Function of the ATP-dependent HslVU Protease in Escherichia coli. The Journal of Biological Chemistry, 273(36), 22929-22935.

Yoo, S. J., Seol, J. H., Shin, D. H., Rohrwild, M., Kang, M. S., Tanaka, K., Goldberg, A. L., and Chung, C. H. (1996). Purification and characterization of the heat shock proteins HslV and HslU that form a new ATP-dependent protease in Escherichia coli. The Journal of Biological Chemistry, 271(24), 14035–14040.

Seol, J. H., Baek, S. H., Kang, M. S., Ha, D. B., and Chung, C. H. (1995). Distinctive roles of the two ATP-binding sites in ClpA, the ATPase component of protease Ti in Escherichia coli. The Journal of Biological Chemistry, 270(14), 8087-8092.

Seong, I. S., Lee, H. R., Seol, J. H., Park, S. K., Lee, C. S., Suh, S. W., Hong, Y. M., Kang, M. S., Ha, D. B., and Chung, C. H. (1994). The P1 reactive site methionine residue of Ecotin is not crucial for its specificity on target proteases. The Journal of Biological Chemistry, 269(34), 21915-21918.

Seol, J. H., Yoo, S. J., Kim, K. I., Kang, M. S., Ha, D. B., and Chung, C. H. (1994). The 65-kDa protein derived from the internal translational initiation site of the clpA gene inhibits the ATP-dependent protease Ti in Escherichia coli. The Journal of Biological Chemistry, 269(47), 29468-29473.

Park, S. K., Kim, K. I., Woo, K. M., Seol, J. H., Tanaka, K., Ichihara, A., Ha, D. B., and Chung, C. H. (1993). Site-directed mutagenesis of the dual translational initiation site of the clpB gene in Escherichia coli and characterization of its gene products. The Journal of Biological Chemistry, 268(27), 20170-20174.