김재범

Kim, Jae Bum

Professor
 Share this to 

김재범

Professor

Kim, Jae Bum

  • Major : Adipocyte and Metabolism
  • Lab. : Laboratory of Adipocyte and Metabolism Research
  • Office : 105-333
  • Office Tel. : +82-2-880-5852
  • Lab Tel. : +82-2-880-4409
  • Website : http://biosci.snu.ac.kr/lamr
  • Email : jaebkim@snu.ac.kr

김재범
Research
Cell Biology Genetics Molecular Biology
1. Mechanism of Adipocyte Differentiation
2. Gene Expression Regulation of Lipogenesis and Insulin-dependent Genes
3. Molecular Mechanisms for Obesity and Diabetes
Education/Career
Education
  • - 1984 - 1988 B.S. Dept. of Zoology, Seoul National University
  • - 1988 - 1990 M.A. Cell & Molecular Biology, Seoul National University
  • - 1991 - 1996 Ph.D. Dept. of Microbiology & Molecular Genetics, Harvard University, U.S.A
Career
  • - 1996- 1997 Postdoctoral Fellow. Dana-Farber Cancer Inst., Harvard Medical School, U.S.A.
  • - 1997 - 2000 Postdoctoral Fellow. Cancer Research Center, Massachusetts Institute of Technology, U.S.A.
  • - 2000 - Present Assistant Professor, Associate Professor, Professor, School of Biological Sciences, Seoul National University
  • - 2004 - Present Associate Member of Korean Academy of Science and Technology
  • - 2005 - 2008 Member of National Bioethics Evaluation, Ministry of Health & Welfare
  • - 2007 - 2008 Visiting Professor, Dept. of Medicine, Univ. of California, San Diego, U.S.A.
  • - 2009 - 2011 Director, Institute of Laboratory Animal Research, Seoul National University, Seoul, Korea
  • - 2011 - 2012 Director, Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Korea
  • - 2011 - Present Director, Center for Adipose Tissue Remodeling, Creative Research Initiatives, Center for Studies on Structure-Function in Adipocyte
  • - 2013 -2014 Member of Presidential Advisory Council on Science & Technology
  • - 2014 - 2015 Visiting Professor/ Project Scientist, Dept. of Pathology, Univ. of California, Los Angeles, U.S.A
  • - 2021 - Present Editor-in-Chief, Molecules and Cells
Publications
  1. Y. S. Lee, P. Li, J. Y. Huh, I. J. Hwang, M. Lu, J. I. Kim, M. Ham, S. Talukdar, A. Chen, W. Lu, G. Bandyopadhyay, R. Schwendener, J. Olefsky, and J. B. Kim*. Inflammation is necessary for long term but not short term HFD-induced insulin resistance. Diabetes, 60:2474-2483. 2011. 10
  2. I. Hwang, Y. J. Park, Y. R. Kim, Y. N. Kim, S Ka, H. Y. Lee, J. K. Seong, Y. J. Seok, and J. B. Kim*. Alteration of gut microbiota by vancomycin and bacitracin improves insulin resistance via glucagon-like peptide 1 in diet-induced obesity. FASEB J., 29:2397-411, 2015. 06. (** This paper has been highlighted in Nat. Rev. Endo. 11:254 [2015])
  3. J. I. Kim, J. Y. Huh, J. H. Sohn, S. S. Choe, Y. S. Lee, C. Y. Lim, A Jo, S. B. Park, W. Han, and J. B. Kim*. Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation. Mol. Cell. Biol., 35:1686-99, 2015.05 (** This paper is selected as a “Spotlight” paper. In the same issue (May 2015, Vol 35, Issue 10), Cover Figure has been selected with our data.)
  4. A. Y. Kim, Y. J. Park, X. Pan, K. C. Shin, S. H. Kwak, A. F. Bassas, R. M. Sallam, K. S. Park, A. A. Alfadda, A. Xu, and J. B. Kim*. Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance. Nat Commun., 6:7585, 2015. 07. (** This paper has been highlighted in Nat. Rev. Endo. 11:504 [2015])
  5. H. Jang, G. Y. Lee, C. P. Selby, G. Lee, Y. G. Jeon, J. H. Lee, K. K. Y. Cheng, P. Titchenell, M. J. Birnbaum, A. Xu, A. Sancar and J. B. Kim* . SREBP1c-CRY1 signaling represses hepatic glucose production by promoting FOXO1 degradation during refeeding. Nat. Commun., 7:12180, 2016.07. (** This paper was invited from Cell Cycle journal for a Commentary Article.)
  6. J. Y. Huh, J. Park, J. I. Kim, Y. J. Park, Y. K. Lee and J. B. Kim*. Deletion of CD1d in Adipocytes Aggravates Adipose Tissue Inflammation and Insulin Resistance in Obesity. Diabetes, 66:835-847, 2017.04. (** This paper was invited from Adipocyte Journal for a Commentary Review.)
  7. K. C. Shin, S. S. Choe, I. J. Hwang, J. Park, J. Yul, J. I. Kim, J. Ching, J.-P. Kovalik and J. B. Kim*. Macrophage VLDLR mediates obesity-induced insulin resistance with adipose tissue inflammation. Nat Commun., 8:1087, 2017. 10.
  8. I. Hwang, K. Jo, K. C. Shin, J. I. Kim, Y. Ji, Y. J. Park, J. Park, Y. G. Jeon, S. Ka, S. Suk, H. L. Noh, S. S. Choe, A. Alfadda, J. K. Kim, S. Kim and J. B. Kim*. GABA stimulated adipose-derived stem cells suppress subcutaneous adipose tissue inflammation in obesity. Proc. Natl. Acad. Sci., 116:11936-11945, 2019. 06.
  9. J. Park, J. Y. Huh, J. Oh, J. I. Kim, S. M. Han, K. C. Shin, Y. G. Jeon, S. S. Choe, J. Park, and J. B. Kim*. Activation of invariant natural killer T cells stimulates adipose tissue remodeling via adipocyte death and birth in obesity. Genes & Dev., 33:1657-1672, 2019. 10.
  10. J. Kong, Y. Ji, Y. G. Jeon, J. S. Han, K. H. Han, J. H. Lee, G. Lee, H. Jang, S. S. Choe, M. Baes and J. B. Kim*. Spatiotemporal contact between peroxisome and lipid droplet regulates fasting-induced lipolysis via PEX5. Nat Commun., DOI: 10.1038/s41467-019-14176-0, 2020. 01.
List