Seoul National University Biological Sciences Website

발표논문

Laboratory of Genes and Development

ACS Chem Biol.

An YJ, Xu WJ, Jin X, Wen H, Kim H, Lee J, Park S (2012). Metabotyping of the C. elegans sir-2.1 Mutant Using in Vivo Labeling and (13)C-Heteronuclear Multidimensional NMR Metabolomics. ACS Chem Biol., (), .

Bio-Protocol

Lee, D., Lee, H., Choi, M. K., Park, S., Lee, J. (2015). Nictation Assays for Caenorhabditis and Other Nematodes. Bio-Protocol, 5(7), e1433.

Biochem Biophys Res Commun

Park MC, Park D, Lee EK, Park T, Lee J. (2010). Genomic analysis of the telomeric length effect on organismic lifespan in Caenorhabditis elegans. Biochem Biophys Res Commun, 396(2), 382-387.

Biochem Biophys Res Commun.

Hong M, Choi MK, Lee J. (2008). The anesthetic action of ethanol analyzed by genetics in Caenorhabditis elegans. Biochem Biophys Res Commun., (), .

Shim J, Lee J (2008). Regulation of rnt-1 expression mediated by the opposing effects of BRO-1 and DBL-1 in the nematode Caenorhabditis elegans. Biochem Biophys Res Commun., (), .

Lee EY, Shim YH, Chitwood DJ, Hwang SB, Lee J, Paik YK (2005). Cholesterol-producing transgenic Caenorhabditis elegans lives longer due to newly acquired enhanced stress resistance. Biochem Biophys Res Commun., (), .

BioEssays

Chuna Kim, Sanghyun Sung, Jun Kim and Junho Lee (2020). Repair and Reconstruction of Telomeric and Subtelomeric Regions and Genesis of New Telomeres: Implications for Chromosome Evolution. BioEssays, (), .

Biotechniques.

Min K, Kang J, Lee J. (2010). A modified feeding RNAi method for simultaneous knock-down of more than one gene in Caenorhabditis elegans. Biotechniques., 48(3), 229-232.

BMC Genomics

Hyunji Lee, Jun Kim, Junho Lee (2023). Benchmarking datasets for assembly-based variant calling using high-fidelity long reads. BMC Genomics, 148(), .

Cell Metab.

Jo H, Shim J, Lee JH, Lee J, Kim JB (2009). IRE-1 and HSP-4 contribute to energy homeostasis via fasting-induced lipases in C. elegans. Cell Metab., 9(5), 440-448.

Cell Reports

Soungyub Ahn, Heeseung Yang, Sangwon Son Hyun Sik Lee, Dongjun Park, Hyunsoo Yim, Hee-Jung Choi, Peter Swoboda,, Junho Lee (2022). The C. elegans regulatory factor X (RFX) DAF-19M module: A shift from general ciliogenesis to cell-specific ciliary and behavioral specialization. Cell Reports, 39(2), .

Curr Biol.

Schroeder NE, Androwski RJ, Rashid A, Lee H, Lee J, Barr MM (2013). Dauer-Specific Dendrite Arborization in C. elegans Is Regulated by KPC-1/Furin. Curr Biol., 23(16), 1527-1535.

Dev Biol.

Kang J, Bai Z, Zegarek MH, Grant BD, Lee J. (2011). Essential roles of snap-29 in C. elegans. Dev Biol., 355(1), 77-88.

Dev Biol..

Ji YJ, Nam S, Jin YH, Cha EJ, Lee KS, Choi KY, Song HO, Lee J, Bae SC, Ahnn J. (2004). RNT-1, the C. elegans homologue of mammalian RUNX transcription factors, regulates body size and male tail development.. Dev Biol.., (), .

Development.

Kang J, Shin D, Yu JR, Lee J. (2009). Lats kinase is involved in the intestinal apical membrane integrity in the nematode Caenorhabditis elegans. Development., 136(16), 2705-2715.

FEBS Lett.

Park JH, Ahn S, Kim S, Lee J, Nam JW, Shin C (2013). Degradome sequencing reveals an endogenous microRNA target in C. elegans. FEBS Lett., 587(7), 964-969.

Kim TH, Hwang SB, Jeong PY, Lee J, Cho JW. (2005). Requirement of tyrosylprotein sulfotransferase-A for proper cuticle formation in the nematode C. elegans. FEBS Lett., (), .

Im SH, Lee J.. (2003). Identification of HMG-5 as a double-stranded telomeric DNA-binding protein in the nematode Caenorhabditis elegans... FEBS Lett., (), .

Shim J, Im SH, Lee J. (2003). Tissue-specific expression, heat inducibility, and biological roles of two hsp16 genes in Caenorhabditis elegans. FEBS Lett., (), .

G3

Sangwon Son, Myung-Kyu Choi, Daisy S Lim, Jaegal Shim, Junho Lee (2022). A genetic screen for aldicarb resistance of Caenorhabditiselegans dauer larvae uncovers 2 alleles of dach-1, a cytochrome P450 gene. G3, 12(12), .

Jiseon Lim, Jun Kim, Junho Lee (2021). Natural variation in reproductive timing and X-chromosome nondisjunction in Caenorhabditis elegans. G3, 11(12), .

Hanee Lee, Junsu Kang and Junho Lee (2018). Involvement of YAP-1, the Homolog of Yes-Associated Protein, in the Wnt-Mediated Neuronal Polarization in Caenorhabditis elegans. G3, 8(8), .

G3 (Bethesda)

Lee K, Shim J, Lee J, Lee J (2013). Identification of Genes Interacting with rnt-1 Through Large-Scale RNAi Screening in Caenorhabditis elegans. G3 (Bethesda), 3(10), 1779-1784.

Genes Dev

Lee J, Jongeward GD, Sternberg PW (1994). unc-101, a gene required for many aspects of Caenorhabditis elegans development and behavior, encodes a clathrin-associated protein.. Genes Dev, (), .

Genetics

Daisy S Lim, Jun Kim, Wonjoo Kim, Nari Kim, Sang-Hee Lee, Daehan Lee, Junho Lee (2023). daf-42 is an evolutionarily young gene essential for dauer development in Caenorhabditis elegans. Genetics, 224(4), .

Hanee Lee, Junsu Kang, Soungyub Ahn and Junho Lee (2019). The Hippo Pathway Is Essential for Maintenance of Apicobasal Polarity in the Growing Intestine of Caenorhabditis elegans. Genetics, (), .

Richaud, Aurélien, Gaotian Zhang, Daehan Lee, Junho Lee, and Marie-Anne Félix. (2018). The Local Co-existence Pattern of Selfing Genotypes in Caenorhabditis elegans Natural Metapopulations. Genetics, 208(2), .

Myung-Kyu Choi, Sangwon Son, Mingi Hong, Min Sung Choi, Jae Young Kwon, Junho Lee (2016). Maintenance of Membrane Integrity and Permeability Depends on a Patched-Related Protein in C. elegans. Genetics, (), .

Cho SW, Lee J, Carroll D, Kim JS, Lee J (2013). Heritable gene knockout in Caenorhabditis elegans by direct injection of Cas9-sgRNA ribonucleoproteins. Genetics, 195(3), 1177-1180.

Genome research

Jiseon Lim, Wonjoo Kim, Jun Kim and Junho Lee (2023). Telomeric repeat evolution in the phylum Nematoda revealed by high-quality genome assemblies and subtelomere structures. Genome Research, 33(11), 1947-1957.

Chuna Kim, Jun Kim, Sunghyun Kim, Daniel E. Cook, Kathryn S. Evans, Erik C. Andersen, and Junho Lee (2019). Long-read sequencing reveals intra-species tolerance of substantial structural variations and new subtelomere formation in C. elegans. Genome research, (), .

Genomics

Kwon JY, Hong M, Choi MS, Kang S, Duke K, Kim S, Lee S, Lee J.. (2004). Ethanol-response genes and their regulation analyzed by a microarray and comparative genomic approach in the nematode Caenorhabditis elegans... Genomics, (), .

J Biochem Mol Biol.

Lee J, Nam S, Hwang SB, Hong M, Kwon JY, Joeng KS, Im SH, Shim J, Park MC. (2004). Functional genomic approaches using the nematode Caenorhabditis elegans as a model system... J Biochem Mol Biol., (), .

J Biol Chem.

Lee J, Lee J (2013). Hypoxia-inducible Factor-1 (HIF-1)-independent Hypoxia Response of the Small Heat Shock Protein hsp-16.1 Gene Regulated by Chromatin-remodeling Factors in the Nematode Caenorhabditis elegans. J Biol Chem., 288(3), 1582-1589.

Lee K, Shim J, Bae J, Kim YJ, Lee J. (2012). Stabilization of RNT-1 Protein, Runt-related Transcription Factor (RUNX) Protein Homolog of Caenorhabditis elegans, by Oxidative Stress through Mitogen-activated Protein Kinase Pathway. J Biol Chem., 287(13), 10444-10452.

Nam S, Min K, Hwang H, Lee HO, Lee JH, Yoon J, Lee H, Park S, Lee J (2009). Control of Rapsyn Stability by the CUL-3-containing E3 Ligase Complex. J Biol Chem., 284(12), 8195-8206.

Lee GE, Yu EY, Cho CH, Lee J, Muller MT, Chung IK.. (2004). DNA-protein kinase catalytic subunit-interacting protein KIP binds telomerase by interacting with human telomerase reverse transcriptase... J Biol Chem., (), .

Kim SH, Hwang SB, Chung IK, Lee J.. (2003). Sequence-specific binding to telomeric DNA by CEH-37, a homeodomain protein in the nematode Caenorhabditis elegans.. J Biol Chem., (), .

J Mol Biol.

Hong M, Kwon JY, Shim J, Lee J. (2004). Differential hypoxia response of hsp-16 genes in the nematode. J Mol Biol., (), .

Hwang SB, Lee J. (2003). Neuron cell type-specific SNAP-25 expression driven by multiple regulatory elements in the nematode Caenorhabditis elegans.. J Mol Biol., (), .

Journal of Biosciences

Daehan Lee, Bo Yun Lee, Myung-Kyu Choi, Nari Kim, Junho Lee (2024). Role of gustatory neurons opposing TGF-β in regulating nictation behavior in Caenorhabditis elegans. Journal of Biosciences, 49(95), .

Journal of Neurogenetics

Heeseung Yang, Bo Yun Lee, Hyunsoo Yim and Junho Lee (2020). Neurogenetics of nictation, a dispersal strategy in nematodes. Journal of Neurogenetics, (), .

Journal of Visualized Experiments

Beomseok Seo, Junho Lee (2016). Observation and Quantification of Telomere and Repetitive Sequences Using Fluorescence In Situ Hybridization (FISH) with PNA Probes in Caenorhabditis elegans. Journal of Visualized Experiments, 114(e54224), .

Mol Cell Biol.

Lee JH, Kong J, Jang JY, Han JS, Ji Y, Lee J, Kim JB (2014). Lipid Droplet Protein LID-1 Mediates ATGL-1-Dependent Lipolysis during Fasting in Caenorhabditis elegans. Mol Cell Biol., 34(22), 4165-4176.

Nam S, Jin YH, Li QL, Lee KY, Jeong GB, Ito Y, Lee J, Bae SC.. (2002). Expression pattern, regulation, and biological role of runt domain transcription factor, run, in Caenorhabditis elegans.. Mol Cell Biol., (), .

Mol Cell.

Hopper NA, Lee J, Sternberg PW. (2000). ARK-1 inhibits EGFR signaling in C. elegans.. Mol Cell., (), .

Mol Cells.

Choi B, Kang J, Park YS, Lee J, Cho NJ. (2011). A possible role for FRM-1, a C. elegans FERM family protein, in embryonic development. Mol Cells., 31(5), 451-459.

Ko E, Lee J, Lee H (2008). Essential role of brc-2 in chromosome integrity of germ cells in C. elegans. Mol Cells., (), .

Im SH, Lee J. (2005). PLP-1 binds nematode double-stranded telomeric DNA. Mol Cells., (), .

Shim J, Lee J. (2005). The AP-3 clathrin-associated complex is essential for embryonic and larval development in Caenorhabditis elegans. Mol Cells., (), .

Shim J, Lee J. (2000). Molecular genetic analysis of apm-2 and aps-2, genes encoding medium and small chains of AP-2 clathrin associated-protein complex in C. elegans.. Mol Cells., (), .

Mol Reprod Dev.

Sternberg, P.W., Lesa, G., Lee, J., Katz, W.S., Yoon, C., Clandinin, T.R., Huang, L.S., Chamberlin, H.M., Jongeward, G. (1995). LET-23-mediated signal transduction during Caenorhabditis elegans development.. Mol Reprod Dev., (), .

NAR Genomics and Bioinformatics

Bo Yun Lee, Jun Kim, Junho Lee (2022). Intraspecific de novo gene birth revealed by presence–absence variant genes in Caenorhabditis elegans. NAR Genomics and Bioinformatics, 4(2), .

Nat Genet.

Joeng KS, Song EJ, Lee KJ, Lee J. (2004). Long lifespan in worms with long telomeric DNA. Nat Genet., (), .

Nat Neurosci.

Lee H, Choi MK, Lee D, Kim HS, Hwang H, Kim H, Park S, Paik YK, Lee J. (2012). Nictation, a dispersal behavior of the nematode Caenorhabditis elegans, is regulated by IL2 neurons. Nat Neurosci., 15(), 107-112.

Nature Communications

Hyunsoo Yim, Daniel T. Choe, J. Alexander Bae, Myung-kyu Choi, Hae-Mook Kang, Ken C. Q. Nguyen, Soungyub Ahn, Sang-kyu Bahn, Heeseung Yang, David H. Hall, Jinseop S. Kim & Junho Lee (2024). Comparative connectomics of dauer reveals developmental plasticity. Nature Communications, 15(1), .

Chuna Kim, Sanghyun Sung, Jong-Seo Kim, Hyunji Lee, Yoonseok Jung, Sanghee Shin, Eunkyeong Kim, Jenny J. Seo, Jun Kim, Daeun Kim, Hiroyuki Niida, V. Narry Kim, Daechan Park and Junho Lee (2021). Telomeres reforged with non-telomeric sequences in mouse embryonic stem cells. Nature Communications, 12(), 1097.

Daehan Lee, Heeseung Yang, Jun Kim, Shannon Brady, Stefan Zdraljevic, Mostafa Zamanian, Heekyeong Kim, Young-ki Paik, Leonid Kruglyak, Erik C. Andersen & Junho Lee (2017). The genetic basis of natural variation in a phoretic behavior. Nature Communications, 8(273), .

B. Seo, C. Kim, M. Hills, S. Sung, H. Kim, E. Kim, D. S. Lim, H. S. Oh, R. M. Choi, J. Chun, J. Shim, J. Lee (2015). Telomere maintenance through recruitment of internal genomic regions. Nature Communications, 6(), 8189.

Nucleic Acids Research

Hyunji Lee, Hiroyuki Niida, Sanghyun Sung, Junho Lee (2024). Haplotype-resolved de novo assembly revealed unique characteristics of alternative lengthening of telomeres in mouse embryonic stem cells. Nucleic Acids Research, (), .

Sanghyun Sung, Eunkyeong Kim, Hiroyuki Niida, Chuna Kim, Junho Lee (2023). Distinct characteristics of two types of alternative lengthening of telomeres in mouse embryonic stem cells. Nucleic Acids Research, (), .

Eunkyeong Kim, Jun Kim, Chuna Kim, and Junho Lee (2021). Long-read sequencing and de novo genome assemblies reveal complex chromosome end structures caused by telomere dysfunction at the single nucleotide level. Nucleic Acids Research, 49(6), 3338–3353.

Oncogene.

Lee J, Ahnn J, Bae SC.. (2004). Homologs of RUNX and CBF beta/PEBP2 beta in C. elegans... Oncogene., (), .

PLoS Comput Biol.

Sohn Y, Choi MK, Ahn YY, Lee J, Jeong J. (2011). Topological Cluster Analysis Reveals the Systemic Organization of the Caenorhabditis elegans Connectome. PLoS Comput Biol., 7(5), Epub.

PNAS

Heeseung Yang, Daehan Lee, Heekyeong Kim, Daniel E. Cook, Young-Ki Paik, Erik C. Andersen, and Junho Lee (2024). Glial expression of a steroidogenic enzyme underlies natural variation in hitchhiking behavior. PNAS, 121(28), .

Cho SC, Park MC, Keam B, Choi JM, Cho Y, Hyun S, Park SC, Lee J. (2010). DDS, 4,4'-diaminodiphenylsulfone, extends organismic lifespan. PNAS, 107(45), 19326-19331.

Kwon JY, Park JM, Gim BS, Han SJ, Lee J, Kim YJ. (1999). Caenorhabditis elegans mediator complexes are required for developmental-specific transcriptional activation.. PNAS, (), .

Science

Yoon, C.H., Lee, J., Jongeward, G.D., Sternberg, P.W. (1995). Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl.. Science, (), .

The Journal of Biological Chemistry

Jung Hyun Lee, Ji Seul Han, Jinuk Kong, Yul Ji, Xuchao Lv, Junho Lee, Peng Li and Jae Bum Kim* (2016). Protein Kinase A subunit balance regulates lipid metabolism in Caenorhabditis elegans and mammalian adipocytes. The Journal of Biological Chemistry, (), .

Worm

Chuna Kim, Sanghyun Sung & Junho Lee (2016). Internal genomic regions mobilized for telomere maintenance in C. elegans. Worm, 5(1), e1146856.