Laboratory of Genes and Development

Laboratory of Genes and Development

Laboratory of Genes and Development

Seoul National University
Laboratory of Genes and Development

Laboratory of Genes and Development

Seoul National University

Laboratory of Genes and Development

Seoul National University

Publications+ more

(2024) Comparative connectomics of dauer reveals developmental plasticity, Nature Communications
(2023) Telomeric repeat evolution in the phylum Nematoda revealed by high-quality genome assemblies and subtelomere structures, Genome Research
(2023) daf-42 is an evolutionarily young gene essential for dauer development in Caenorhabditis elegans, Genetics
(2023) Distinct characteristics of two types of alternative lengthening of telomeres in mouse embryonic stem cells, Nucleic Acids Research
(2023) Benchmarking datasets for assembly-based variant calling using high-fidelity long reads, BMC Genomics
(2022) A genetic screen for aldicarb resistance of Caenorhabditiselegans dauer larvae uncovers 2 alleles of dach-1, a cytochrome P450 gene, G3
(2022) Intraspecific de novo gene birth revealed by presence–absence variant genes in Caenorhabditis elegans, NAR Genomics and Bioinformatics
(2022) The C. elegans regulatory factor X (RFX) DAF-19M module: A shift from general ciliogenesis to cell-specific ciliary and behavioral specialization, Cell Reports
(2021) Natural variation in reproductive timing and X-chromosome nondisjunction in Caenorhabditis elegans, G3
(2021) Long-read sequencing and de novo genome assemblies reveal complex chromosome end structures caused by telomere dysfunction at the single nucleotide level, Nucleic Acids Research

Welcome to the
"Laboratory of Genes and Development"

Our lab utilizes molecular genetics in Caenorhabditis elegans to investigate various topics related to the nervous system, transcriptional regulation, and telomeres. C. elegans is a useful experimental system due to its ease of maintenance, transparency that allows for visual examination of its inner workings via microscopy, availability of genetic methods, a simpler nervous system that exhibits complex behaviors, and conservation of many genes with human counterparts.