Emeritus Professor
Roe, Jung-Hye
Research
Genomics
Microbiology
Molecular Biology
Microbial Response to Environmental Changes
1. Regulation of Growth and Differentiation of antibiotics-producing bacteria Streptomyces coelicolor; interplay with redox and stress regulation
● Roles of multiple sigmas and anti-sigma factors
● Regulator of anti-oxidative enzymes
● Response to redox-active drugs
2. Role of mitochondrial function and oxidative stress response in the growth and sexual development of Schizosaccharomyces pombe
● Regulation of Iron homeostasis and iron cofactor generation
● Genomic study of genes encoding mitochondrial functions
● Regulation of long-term survival and meiosis
3. Genomic analysis of lactic acid bacteria from kimchi
1. Regulation of Growth and Differentiation of antibiotics-producing bacteria Streptomyces coelicolor; interplay with redox and stress regulation
● Roles of multiple sigmas and anti-sigma factors
● Regulator of anti-oxidative enzymes
● Response to redox-active drugs
2. Role of mitochondrial function and oxidative stress response in the growth and sexual development of Schizosaccharomyces pombe
● Regulation of Iron homeostasis and iron cofactor generation
● Genomic study of genes encoding mitochondrial functions
● Regulation of long-term survival and meiosis
3. Genomic analysis of lactic acid bacteria from kimchi
Education/Career
Education
- - 1979.9 - 1984.12 Ph.D., University of Wisconsin, Madison, Molecular Biology Program
- - 1975.3 - 1979.2 BS, Seoul National University, Dept. of Microbiology
Career
- - 2018 - 2021 President, National Research Foundation of Korea
- - 2012 - present advisory board, Molecular Microbiology
- - 2012 - 2017 Editorial board, Annual Review of Microbiolology
- - 2012 - 2015 Editorial board, J. Bacteriology
- - 2010 - present Fellow, American Academy of Microbiology
- - 2009 - present Director, BK21 program for Biological Sciences, SNU
- - 2009 - present Chair, School of Biological Sciences, Seoul National University
- - 2007 - 2011 Editorial board, Microbiology
- - 2004 - 2006 Dean, Office of Research Affairs, Seoul National University
- - 2000 - 2022 Professor, School of Biological Sciences, Seoul National University
- - 1997-1999 Vice Dean, College of Natural Sciences, Seoul National University
- - 1986 - 1999 Assistant, Associate, Full Professor, Dept. of Microbiology, College of Natural Sciences, Seoul National University
- - 1984 - 1986 Research Associate, McArdle Laboratory for Cancer Research, UW-Madison
Publications
- Lee JH, Yoo JS, Kim Y, Kim JS, Lee EJ, Roe JH. (2020). The WblC/WhiB7 transcription factor controls intrinsic resistance to translation-targeting antibiotics by altering ribosome composition. mBio
- Kim JE, Choi JS, Kim JS, Cho YH, Roe JH. (2020). Lysine acetylation of the housekeeping sigma factor enhances the activity of the RNA polymerase holoenzyme. Nucleic Acids Res
- Kim EJ, Cho YJ, Chung WH, Roe JH. (2020). The role of Rsv1 in the transcriptional regulation of genes involved in sugar metabolism for long-term survival. FEBS J
- Park JH, Lee JH, Roe JH. (2019). SigR, a hub of multilayered regulation of redox and antibiotic stress responses. Mol Microbiol
- Jung SJ, Choi Y, Lee D, Roe JH. (2019). Nuclear aconitase antagonizes heterochromatic silencing by interfering with Chp1 binding to DNA. Biochem Biophys Res Commun