박주홍

Park, Joo-Hong

Assistant Professor

박주홍

Assistant Professor

Park, Joo-Hong

박주홍
Research
Immunology Microbiology Molecular Biology
The mammalian host accommodates trillions of bacteria, many of which provide beneficial effects to the host, including protection from pathogenic microorganisms and essential metabolites. It has been shown that the gut microbiome regulates differentiation and function of immune cells, which are critical for symbiotic relationship and host health. My research aims at understanding reciprocal interactions between the microbiome and the host immune system to establish symbiosis and homeostasis. To achieve this goal, I focus on:

1. Impact of the microbiome on the development of host immune system
2. Roles of innate/adaptive immune system in maintaining symbiosis between the microbiome and hosts. 
3. Elucidation of symbiotic bacteria and their genes involved in host health and disease
Education/Career
Education
  • - 2008 Ph.D. : School of Biological Sciences, Seoul National University
  • - 2001 B.S. : Department of Microbiology, Seoul National University
Career
  • - 2018-present Assistant Professor, School of Biological Sciences, Seoul National University
  • - 2013-2018 Postdoctoral Fellow, Institut Pasteur (Paris)
  • - 2012-2013 Research Assistant Professor, College of Medicine, Yonsei University
  • - 2010-2012 Postdoctoral Fellow, College of Medicine, Yonsei University
  • - 2008-2010 Senior Researcher, Institute of Microbiology, Seoul National University
Publications
  1. Ohnmacht C*, Park JH*, Cording S, Wing JB, Atarashi K, Obata Y, Gaboriau-Routhiau V, Marques R, Dulauroy S, Fedoseeva M, Busslinger M, Cerf-Bensussan N, Boneca IG, Voehringer D, Hase K, Honda K, Sakaguchi S, Eberl G. 2015. The microbiota regulates type 2 immunity through RORγt+ T cells. Science. 349(6251):989-93 (* contributed equally)
  2. Park JH, Choi Y, Song MJ, Park K, Lee JJ, Kim HP. 2016. Dynamic long-range chromatin interaction controls expression of IL-21 in CD4+ T cells. Journal of Immunology. 196(10):4378-89.
  3. Park JH* and Eberl G*. 2018. Type 3 regulatory T cells at the interface of symbiosis. Journal of Microbiology. 56(3):163-171. (* co-corresponding authors)
  4. Park JH, Lee JH and Roe JH. 2019. SigR, a hub of multilayered regulation of redox and antibiotic stress responses. Molecular Microbiology. 112(2):420-431.
  5. Seo B, Jeon K, Moon S, Lee K, Kim WK, Jeong H, Cha KH, Lim MY, Kang W, Kweon MN, Sung J, Kim W, Park JH and Ko G. 2020. Roseburia spp. abundance associates with alcohol consumption in humans and its administration ameliorate alcoholic fatty liver in mice. Cell Host Microbe. 27(1):25-40.