노정혜

Professor

Roe, Jung-Hye

노정혜
Research
Genomics Microbiology Molecular Biology
Microbial Response to Environmental Changes
1. Regulation of Growth and Differentiation of antibiotics-producing bacteria Streptomyces coelicolor; interplay with redox and stress regulation
● Roles of multiple sigmas and anti-sigma factors
● Regulator of anti-oxidative enzymes
● Response to redox-active drugs
2. Role of mitochondrial function and oxidative stress response in the growth and sexual development of Schizosaccharomyces pombe
● Regulation of Iron homeostasis and iron cofactor generation
● Genomic study of genes encoding mitochondrial functions
● Regulation of long-term survival and meiosis
3. Genomic analysis of lactic acid bacteria from kimchi
Education/Career
Education
  • - 1979.9 - 1984.12 Ph.D., University of Wisconsin, Madison, Molecular Biology Program
  • - 1975.3 - 1979.2 BS, Seoul National University, Dept. of Microbiology
Career
  • - 2018 - present President, National Research Foundation of Korea
  • - 2012 - present advisory board, Molecular Microbiology
  • - 2012 - 2017 Editorial board, Annual Review of Microbiolology
  • - 2012 - 2015 Editorial board, J. Bacteriology
  • - 2010 - present Fellow, American Academy of Microbiology
  • - 2009 - present Director, BK21 program for Biological Sciences, SNU
  • - 2009 - present Chair, School of Biological Sciences, Seoul National University
  • - 2007 - 2011 Editorial board, Microbiology
  • - 2004 - 2006 Dean, Office of Research Affairs, Seoul National University
  • - 2000 - present Professor, School of Biological Sciences, Seoul National University
  • - 1997-1999 Vice Dean, College of Natural Sciences, Seoul National University
  • - 1986 - 1999 Assistant, Associate, Full Professor, Dept. of Microbiology, College of Natural Sciences, Seoul National University
  • - 1984 - 1986 Research Associate, McArdle Laboratory for Cancer Research, UW-Madison
Publications
  1. Lee JH, Yoo JS, Kim Y, Kim JS, Lee EJ, Roe JH. (2020). The WblC/WhiB7 transcription factor controls intrinsic resistance to translation-targeting antibiotics by altering ribosome composition. mBio
  2. Kim JE, Choi JS, Kim JS, Cho YH, Roe JH. (2020). Lysine acetylation of the housekeeping sigma factor enhances the activity of the RNA polymerase holoenzyme. Nucleic Acids Res
  3. Kim EJ, Cho YJ, Chung WH, Roe JH. (2020). The role of Rsv1 in the transcriptional regulation of genes involved in sugar metabolism for long-term survival. FEBS J
  4. Park JH, Lee JH, Roe JH. (2019). SigR, a hub of multilayered regulation of redox and antibiotic stress responses. Mol Microbiol
  5. Jung SJ, Choi Y, Lee D, Roe JH. (2019). Nuclear aconitase antagonizes heterochromatic silencing by interfering with Chp1 binding to DNA. Biochem Biophys Res Commun