Laboratory of Molecular & Cellular Signaling

Laboratory of Molecular & Cellular Signaling

Seoul National University
Laboratory of Molecular & Cellular Signaling

Laboratory of Molecular & Cellular Signaling

Seoul National University
Laboratory of Molecular & Cellular Signaling

Laboratory of Molecular & Cellular Signaling

Seoul National University

News & Notice+ more

Publications+ more

(2019) Quantification of the dynamic phosphorylation process of ERK using stable isotope dilution selective reaction monitoring mass spectrometry, Proteomics
(2017) Identification of PTPN1 as a novel negative regulator of the JNK MAPK pathway using a synthetic screening for pathway-specific phosphatases, Sci Rep.
(2016) A conserved tyrosine residue in MAPKK Ste7 regulates kinase activity during mating signal transduction, The American Society for Cell Biology
(2016) Adjustable under-expression of yeast mating pathway proteins in Saccharomyces cerevisiae using a programmed ribosomal frameshift, Appl Microbiol Biotechnol.
(2016) Screening and identification of dissociative inhibitors of ERK MAP kinase signaling pathway, KSBMB
(2015) Simple synthetic protein scaffolds can create adjustable artificial MAPK circuits in yeast and mammalian cells, Sci. Signal.
(2015) Identification of novel benzenediamine-based inhibitor of Tau fibrous aggregation associated with Alzheimer’s disease, 한국분자·세포생물학회
(2015) Analysis of nitrated proteins in Saccharomyces cerevisiae involved in mating signal transduction, Proteomics
(2014) Screening and identification of dissociative inhibitors of ERK MAP kinase signaling pathway., The American Society for Cell Biology
(2014) Reassembly of JIP1 scaffold complex in JNK MAP kinase pathway using heterologous protein interactions, PLoS One

Welcome to the
"Laboratory of Molecular & Cellular Signaling"

We are broadly interested in signal transduction circuits inside cells. Our research interests are; 1. Understanding the fundamental mechanisms of cellular signaling 2. Artificial rewiring of the cellular signaling networks via manipulation of protein-protein interactions 3. Pathway engineering & pathway disruption