Seoul National University Biological Sciences Website

Publications

Laboratory of Protein Biochemistry

Animal Cells and Systems

Seong Won Lee, Min Woo Seong, Young Joo Jeon & Chin Ha Chung (2012). Ubiquitin E3 ligases controlling p53 stability. Animal Cells and Systems, (), .

Atherosclerosis

Lim S, Ahn BY, Chung SS, Park HS, Cho BJ, Kim M, Choi SH, Lee IK, Lee SW, Choi SJ, Chung CH, Cho YM, Lee HK, Park KS (2009). Effect of a peroxisome proliferator-activated receptor gamma sumoylation mutant on neointimal formation after balloon injury in rats. Atherosclerosis, (), .

Biochem J

Kim, S. S., Kim, J. H., Kim, H. S., Park, D. E., and Chung, C. H. (2000). Involvement of the theta-type protein kinase C in translocation of myristoylated alanine-rich C kinase substrate (MARCKS) during myogenesis of chick embryonic myoblasts. Biochem J, 347(), 139-146.

Park, K. C., Choi, E. J., Min, S. W., Chung, S. S., Kim, H., Suzuki, T., Tanaka, K., and Chung, C. H. (2000). Tissue-specificity, functional characterization and subcellular localization of a rat ubiquitin-specific processing protease, UBP109, whose mRNA expression is developmentally regulated. Biochem J, 349(), 443-453.

Biochim Biophys Acta

Jeon YJ, Yoo HM, Chung CH. (2010) ISG15 and immune diseases (2010). ISG15 and immune diseases. Biochim Biophys Acta, 1802(5)(), 485-496.

Cell Death & Differentiation

Oh KH, Yang SW, Park JM, Seol JH, Iemura S, Natsume T, Murata S, Tanaka K, Jeon YJ, Chung CH (2011). Control of AIF-mediated cell death by antagonistic functions of CHIP ubiquitin E3 ligase and USP2 deubiquitinating enzyme. Cell Death & Differentiation, (), .

EMBO

Jeon YJ, Choi JS, Lee JY, Yu KR, Kim SM, Ka SH, Oh KH, Kim KI, Zhang DE, Bang OS, Chung CH. (2009). ISG15 modification of filamin B negatively regulates the type I interferon-induced JNK signalling pathway. EMBO, 10(4)(), 374-80.

Comment on Jeon YJ et al, Whitmarsh AJ (2009). Filamin B: a scaffold for interferon signalling. EMBO, 10(4)(), 349-51.

Embo J

Kang, M. S., Kim, S. R., Kwack, P., Lim, B. K., Ahn, S. W., Rho, Y. M., Seong, I. S., Park, S. C., Eom, S. H., Cheong, G. W., and Chung, C. H (2003). Molecular architecture of the ATP-dependent CodWX protease having an N-terminal serine active site. Embo J, 22(), 2893-2902.

Kang, M. S., Lim, B. K., Seong, I. S., Seol, J. H., Tanahashi, N., Tanaka, K., and Chung, C. H. (2001). The ATP-dependent CodWX (HslVU) protease in Bacillus subtilis is an N-terminal serine protease. Embo J, 20(), 734-742.

EMBO Journal

Seong Won Lee, Moon Hee Lee, Jong Ho Park, Sung Hwan Kang, Hee Min Yoo, Seung Hyun Ka, Young Mi Oh, Young Joo Jeon* and Chin Ha Chung* (2012). SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage. EMBO Journal, (), .

FEBS Lett

Seong, I. S., Oh, J. Y., Lee, J. W., Tanaka, K., and Chung, C. H (2000). The HslU ATPase acts as a molecular chaperone in prevention of aggregation of SulA, an inhibitor of cell division in Escherichia coli. FEBS Lett, 477(), 224-229.

Genes Cells

Lee, J., Jee, C., Lee, J. I., Lee, M. H., Lee, M. H., Koo, H. S., Chung, C. H., Ahnn, J (2001). A deubiquitinating enzyme, UCH/CeUBP130, has an essential role in the formation of a functional microtubule-organizing centre (MTOC) during early cleavage in C. elegans. Genes Cells, 6(), 899-911.

J Biochem (Tokyo)

Kim, J. H., Park, K. C., Chung, S. S., Bang, O., and Chung, C. H. (2003). Deubiquitinating enzymes as cellular regulators. J Biochem (Tokyo), 134(), 9-18.

J Biol Chem

Lee GH, Kim DS, Kim HT, Lee JW, Chung CH, Ahn T, Lim JM, Kim IK, Chae HJ, Kim HR. (2011). Enhanced lysosomal activity is involved in Bax inhibitor-1-induced regulation of the endoplasmic reticulum (ER) stress response and cell death against ER stress: involvement of vacuolar H+-ATPase (V-ATPase).. J Biol Chem, (), .

Tatsumi K, Sou YS, Tada N, Nakamura E, Iemura S, Natsume T, Kang SH, Chung CH, Kasahara M, Kominami E, Yamamoto M, Tanaka K, Komatsu M (2010). A novel type of E3 ligase for the Ufm1 conjugation system. J Biol Chem, 285(8)(), 5417-27.

Lee JW, Park E, Jeong MS, Jeon YJ, Eom SH, Seol JH, Chung CH (2009). HslVU ATP-dependent protease utilizes maximally six among twelve threonine active sites during proteolysis. J Biol Chem, 284(48)(), 33475-84.

Park E, Lee JW, Eom SH, Seol JH, Chung CH. (2008). Binding of MG132 or deletion of the Thr active sites in HslV subunits increases the affinity of HslV protease for HslU ATPase and makes this interaction nucleotide-independent. J Biol Chem, 283(48)(), ):33258-66.

Ha BH, Ahn HC, Kang SH, Tanaka K, Chung CH, Kim EE (2008). Structural basis for Ufm1 processing by UfSP1. J Biol Chem, 283(21)(), 14893-900.

Kang, S. H., Kim, G. R., Seong, I. S., Baek, S. H., Seol, J. H., Bang, O. S., Ovaa, H., Tatsumi, K., Komatsu, M., Tanaka, K., Chung, C. H. (2007). Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2. J Biol Chem, 282(8)(), 5256-62.

Park, E., Rho, Y. M., Koh, O. J., Ahn, S. W., Seong, I. S., Song, J. J., Bang, O., Seol, J. H., Wang, J., Eom, S. H., and Chung, C. H. (2005). Role of the GYVG pore motif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase. J Biol Chem, 280(), 22892-22898.

Seong, I. S., Kang, M. S., Choi, M. K., Lee, J. W., Koh, O. J., Wang, J., Eom, S. H., and Chung, C. H. (2002). The C-terminal tails of HslU ATPase act as a molecular switch for activation of HslV peptidase. J Biol Chem, 277(), 25976-25982.

Cho, E. G., Kim, M. G., Kim, C., Kim, S. R., Seong, I. S., Chung, C., Schwartz, R. H., and Park, D. (2001). N-terminal processing is essential for release of epithin, a mouse type II membrane serine protease. J Biol Chem, 276(), 44581-44589.

Kim, K. I., Baek, S. H., Jeon, Y. J., Nishimori, S., Suzuki, T., Uchida, S., Shimbara, N., Saitoh, H., Tanaka, K., and Chung, C. H (2000). A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs. J Biol Chem, 275(), 14102-14106.

J Cell Sci

Kim, S. S., Kim, J. H., Lee, S. H., Chung, S. S., Bang, O. S., Park, D., and Chung, C. H. (2002). Involvement of protein phosphatase-1-mediated MARCKS translocation in myogenic differentiation of embryonic muscle cells. J Cell Sci, (), .

J Clin Invest.

Jeon YJ, Jo MG, Yoo HM, Hong SH, Park JM, Ka SH, Oh KH, Seol JH, Jung YK, Chung CH. (2012). Chemosensitivity is controlled by p63 modification with ubiquitin-like protein ISG15. J Clin Invest., (), .

J Mol Biol

Kim, K. I., Cheong, G. W., Park, S. C., Ha, J. S., Woo, K. M., Choi, S. J., and Chung, C. H. (2000). Heptameric ring structure of the heat-shock protein ClpB, a protein-activated ATPase in Escherichia coli. J Mol Biol, 303(), 656-666.

J. Biol. Chem

Kwon, J. E., La, M., Oh, K. H., Oh, Y. M., Kim, G. R., Seol, J. H., Baek, S. H., Chiba, T., Tanaka, K., Bang, O. S., Joe, C. O., and Chung, C. H (2006). SPOP BTB protein serves as an adaptor of Daxx for ubiquitination by Cul3-based ubiquitin ligase. J. Biol. Chem, 281(), 12664-12672.

Choi, S. J., Chung, S. S., Rho, E. J., Lee, H. W., Lee, M. H., Choi, H. S., Seol, J. H., Baek, S. H., Bang, O. S., and Chung, C. H. (2006). Negative modulation of RXRa transcriptional activity by SUMO modification and its reversal by SUMO-specific protease SUSP1.. J. Biol. Chem, 281(), 30669-30677.

Journal of Molecular Biology

Eunyong Park, Jung Wook Lee, Hee Min Yoo1, Byung Hak Ha, Jun Yop An, Young Joo Jeon, Jae Hong Seol, Soo Hyun Eom, Chin Ha Chung (2013). Structural alteration in the pore motif of the bacterial 20S proteasome homolog HslV leads to uncontrolled protein degradation. Journal of Molecular Biology, (), .

Journal of Neuroscience

Seung Wook Yang, Kyu Hee Oh, Esther Park, Hyun Min Chang, Jung Mi Park, Min Woo Seong, Seung Hyeun Ka, Woo Keun Song, Dong Eun Park, Peter W. Baas, Young Joo Jeon and Chin Ha Chung (2013). USP47 and CHIP antagonistically regulate katanin-p60-mediated axonal growth. Journal of Neuroscience, (), .

Methods Enzymol

Kang, S. H., Park, J. J., Chung, S. S., Bang, O. S., and Chung, C. H. (2005). Strategies for assaying deubiquitinating enzymes.. Methods Enzymol, 398(), 500-508.

Mol Biol Cell

Jeon YJ, Choi JS, Lee JY, Yu KR, Ka SH, Cho Y, Choi EJ, Baek SH, Seol JH, Park D, Bang OS, Chung CH (2008). Filamin B serves as a molecular scaffold for type I interferon-induced c-Jun NH2-terminal kinase signaling pathway. Mol Biol Cell, 19(12)(), 5116-30.

Mol Cell

Lee JM, Lee JS, Kim H, Kim K, Park H, Kim JY, Lee SH, Kim IS, Kim J, Lee M, Chung CH, Seo SB, Yoon JB, Ko E, Noh DY, Kim KI, Kim KK, Baek SH. (2012). EZH2 Generates a Methyl Degron that Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex.. Mol Cell, (), .

Mol Cell Biol

Chung SS, Ahn BY, Kim M, Choi HH, Park HS, Kang S, Park SG, Kim YB, Cho YM, Lee HK, Chung CH, Park KS (2010). Control of adipogenesis by the SUMO-specific protease SENP2. Mol Cell Biol, 30(9)(), 2135-46.

Lee J, Lee Y, Lee MJ, Park E, Kang SH, Chung CH, Lee KH, Kim K (2008). Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol Cell Biol, 28(19)(), 6056-65.

Mol Cells

Lee JW, Park E, Bang O, Eom SH, Cheong GW, Chung CH, Seol JH. (2007). Nucleotide triphosphates inhibit the degradation of unfolded proteins by HslV peptidase. Mol Cells, 23(2)(), 252-257.

Mol. Cells

Park, S. C., Jia, B., Yang, J. K., Van D. L., Shao, Y. G., Han S. W., Jeon, Y. J., Chung, C. H., and Cheong G. W (2006). Oligomeric structure of the ATP-dependent protease La (Lon) of Escherichia coli. Mol. Cells, 21(), 129-134.

Molecular Cell

Yoo HM, Kang SH, Kim JY, Lee JE, Seong MW, Lee SW, Ka SH, Sou YS, Komatsu M, Tanaka K, Lee ST, Noh DY, Baek SH, Jeon YJ, Chung CH. (2014). Modification of ASC1 by UFM1 Is Crucial for ERα Transactivation and Breast Cancer Development. Molecular Cell, (), .

Jung Mi Park, Seung Wook Yang, Kyung Ryun Yu, Seung Hyun Ka, Seong Won Lee, Jae Hong Seol, Young Joo Jeon,and Chin Ha Chung (2014). Modification of PCNA by ISG15 plays a crucial role in termination of error-prone translesion DNA synthesis. Molecular Cell, (), .

Nat Cell Biol

Oh YM, Kwon YE, Kim JM, Bae SJ, Lee BK, Yoo SJ, Chung CH, Deshaies RJ, Seol JH (2009). Chfr is linked to tumour metastasis through the downregulation of HDAC1. Nat Cell Biol, 11(3)(), 295-302.

Nat. Cell Biol

Kim, J. H., Choi, H. J., Kim, B., Lee, J. M., Kim, I. S., Lee, M. H., Choi, S. J., Kim, M. H., Kim, K. I., Kim, S. I., Chung, C. H., and Baek, S. H (2006). SUMO modification of a reptin chromatin remodeling complex reveals a new signal integration code in cancer metastasis. Nat. Cell Biol, 8(), 631-639.

Nat. Cell Biol.

Moon Hee Lee, Sung Won Lee, Eun Joo Lee, Soo Joon Choi, Sung Soo Chung, Jae Il Lee, Joong Myung Cho, Jae Hong Seol, Sung Hee Baek, Keun Il Kim, Tomoki Chiba, Keiji Tanaka, Ok Sun Bang and Chin Ha Chung (2006). SUMO-specific protease SUSP4 positively regulates p53 tumor suppressor by promoting self-ubiquitination of Mdm2. Nat. Cell Biol., 8(), 1424-1431.

Nature

Kim, J. H., Kim, B., Cai, L., Choi, H. J., Ohgi, K. A., Tran, C., Chen, C., Chung, C. H., Huber, O., Rose, D. W., et al. (2005). Transcriptional regulation of a metastasis suppressor gene by Tip60 and beta-catenin complexes. Nature, 434(), 921-926.

nature communication

Kanako Tatsumi, Harumi Yamamoto-Mukai, Ritsuko Shimizu, Satoshi Waguri, Yu-Shin Sou, Ayako Sakamoto, Choji Taya, Hiroshi Shitara, Takahiko Hara, Chin Ha Chung, Keiji Tanaka, Masayuki Yamamoto & Masaaki Komatsu (2011). The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice. nature communication, (), .

Nature Communications

JH Park, SW Lee, SW Yang, HM Yoo, JM Park, MW Seong, SH Ka, KH Oh, YJ Jeon, CH Chung (2014). Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage. Nature Communications, (), .

PNAS

Kim JH, Lee JM, Nam HJ, Choi HJ, Yang JW, Lee JS, Kim MH, Kim SI, Chung CH, Kim KI, Baek SH (2007). SUMOylation of pontin chromatin-remodeling complex reveals a signal integration code in prostate cancer cells. PNAS, 104(52)(), 20793-8.

Proc Natl Acad Sci U S A

Park, K. C., Kim, J. H., Choi, E. J., Min, S. W., Rhee, S., Baek, S. H., Chung, S. S., Bang, O., Park, D., Chiba, T., et al. (2002). Antagonistic regulation of myogenesis by two deubiquitinating enzymes, UBP45 and UBP69. Proc Natl Acad Sci U S A, (), .

Proteins

Rho SH, Park HH, Kang GB, Im YJ, Kang MS, Lim BK, Seong IS, Seol J, Chung CH, Wang J, Eom SH (2008). Crystal structure of Bacillus subtilis CodW, a noncanonical HslV-like peptidase with an impaired catalytic apparatus. Proteins, 71(2)(), 1020-1026.

Structure

Wang, J., Song, J. J., Seong, I. S., Franklin, M. C., Kamtekar, S., Eom, S. H., Chung, C. H. (2001). Nucleotide-dependent conformational changes in a protease-associated ATPase HsIU. Structure, 9(), 1107-1116.

Wang, J., Song, J. J., Franklin, M. C., Kamtekar, S., Im, Y. J., Rho, S. H., Seong, I. S., Lee, C. S., Chung, C. H., and Eom, S. H (2001). Crystal structures of the HslVU peptidase-ATPase complex reveal an ATP-dependent proteolysis mechanism. Structure, 9(), 177-184.

The Journal of Biological Chemistry

Ha BH, Jeon YJ, Shin SC, Tatsumi K, Komatsu M, Tanaka K, Watson CM, Wallis G, Chung CH, Kim EE (2011). Structure of Ubiquitin-fold modifier 1 specific protease, UfSP2. The Journal of Biological Chemistry, (), .

예전 논문들

Chung CH (0). 1997- 1999. 예전 논문들, (), .