Adipocyte
Am. J. Physiol. Endoc. M.
Arterioscler. Thromb. Vasc. Biol.
Je-Won Ryu, Kyung Hee Hong, Jin Hee Maeng, Jae-Bum Kim, Jesang Ko, Joong Yeol Park, Ki-Up Lee, Myeong Ki Hong, Seong Wook Park, You Ho Kim, Ki Hoon Han, "Overexpression of uncoupling protein 2 in THP1 monocytes inhibits beta2 integrin-mediated firm adhesion and transendothelial migration," Arterioscler. Thromb. Vasc. Biol., May, 2004.
Biochem. Biophys. Res. Commun.
Biochem. J.
Biochim. Biophys. Acta.
Biochimie
Bioorg. Med. Chem.
Cell Cycle
Cell Death Differ.
Cell Death Dis.
Cell Metab.
Gung Lee, Ye Young Kim, Hagoon Jang, Ji Seul Han, Hahn Nahmgoong, Yoon Jeong Park, Sang Mun Han, Changyun Cho, Sangsoo Lim, Jung-Ran Noh, Won Keun Oh, Chul-Ho Lee, Sun Kim, Jae Bum Kim., "SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance in obesity.," Cell Metab., March, 2022.
Hahn Nahmgoong, Yong Geun Jeon, Eun Seo Park, Yoon Ha Choi, Sang Mun Han, Jeu Park, Yul Ji,
Jee Hyung Sohn, Ji Seul Han, Ye Young Kim, Injae Hwang, Yun Kyung Lee, Jin Young Huh, Sung Sik Choe, Tae Jung Oh, Sung Hee Choi, Jong Kyoung Kim, and Jae Bum Kim, "Distinct Properties of Adipose Stem Cell Subpopulations Determine Fat Depot-Specific Characteristics," Cell Metab., March, 2022.
(*The cover of the same issue highlights this study. ** This paper has been highlighted in Nat. Rev. Endocrinol. 18:133 [2022])
Cell Rep.
Chan Hee Lee, Hyo Jin Kim, Yong-Soo Lee, Gil Myoung Kang, Hyo Sun Lim, Seung-hwan Lee, Do Kyeong Song, Obin Kwon, Injae Hwang, Myeongjoo Son, Kyunghee Byun, Young Hoon Sung, Seyun Kim, Jae Bum Kim, Eun Young Choi, Young-Bum Kim, Keetae Kim, Mi-Na Kweon, Jong-Woo Sohn, and Min-Seon Kim, "Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation.," Cell Rep., October, 2018.
Cell Reports
Kyung Cheul Shin, Jin Young Huh, Yul Ji, Ji Seul Han, Sang Mun Han, Jeu Park, Hahn Nahmgoong, Won Taek Lee, Yong Geun Jeon, Bohyeon Kim, Chanyoon Park, Heonjoong Kang, Sung Sik Choe, and Jae Bum Kim, "VLDL-VLDLR axis facilitates brown fat thermogenesis through replenishment of lipid fuels and PPAR/δ activation.," Cell Reports, December, 2022.
ChemMedChem
Circ. Res.
Circulation
Ki Hoon Han, Jewon Ryu, Kyung Hee Hong, Jesang Ko, Youngmi Kim Pak, Jae-Bum Kim, Seong Wook Park and Jae Joong Kim, "HMG-CoA reductase inhibition reduces monocyte CC chemokine receptor 2 expression and monocyte chemoattractant protein-1-mediated monocyte recruitment in vivo," Circulation, March, 2005.
Contact
Curr. Opin. Cell. Biol.
Curr. Opin. Lipidol.
Diabetes
Ye Young Kim, Hagoon Jang, Gung Lee, Yong Geun Jeon, Jee Hyung Sohn, Ji Seul Han, Won Taek Lee, Jeu Park, Jin Young Huh, Hahn Nahmgoong, Sang Mun Han, Jeesoo Kim, Minwoo Pak, Sun Kim, Jong-Seo Kim, and Jae Bum Kim, "Hepatic GSK3β-dependent CRY1 Degradation Contributes to Diabetic Hyperglycemia.," Diabetes, July, 2022.
Young Jin, Yul Ji, Yaechan Song, Sung Sik Choe, Yong Geun Jeon, Heeju Na, Tae Wook Nam,
Hye Jeong Kim, Hahn Nahmgoong, Sung Min Kim, Jae-woo Kim, Ki Taek Nam, Je Kyung Seong,
Daehee Hwang, Chan Bae Park, In Hye Lee, Jae Bum Kim, and Han-Woong Lee, "Depletion of adipocyte Becn1 leads to lipodystrophy and metabolic dysregulation.," Diabetes, January, 2021.
Yong Geun Jeon, Jae Ho Lee, Yul Ji, Jee Hyung Sohn, Dabin Lee, Dong Wook Kim, Seul Gi Yoon,
Kyung Cheul Shin, Jeu Park, Je Kyung Seong, Je-Yoel Cho, Sung Sik Choe, and Jae Bum Kim, "RNF20 Functions as a Transcriptional Coactivator for PPARγ by Promoting NCoR1 Degradation in Adipocytes.," Diabetes, January, 2020.
(**The figure on this paper has been selected as a cover figure in the same issue (January 2020, Vol 69, Issue 1)
Mira Ham, Sung Sik Choe, Kyung Cheul Shin, Goun Choi, Ji-Won Kim,
Jung-Ran Noh, Yong-Hoon Kim, Je-won Ryu, Kun-Ho Yoon, Chul-Ho Lee,
and Jae Bum Kim, "Glucose-6-phosphate dehydrogenase deficiency improves insulin resistance with reduced adipose tissue inflammation in obesity," Diabetes, September, 2016.
(** This paper was invited from Adipocyte journal for a Commentary Review.)
Yun Sok Lee, Pingping Li, Jin Young Huh, In Jae Hwang, Min Lu, Jong In Kim, Mira Ham, Saswata Talukdar, Ai Chen, Wendell J. Lu, Guatam K. Bandyopadhyay, Reto Schwendener, Jerrold Olefsky, and Jae Bum Kim, "Inflammation is necessary for long term but not short term HFD-induced insulin resistance," Diabetes, October, 2011.
Hyun Woo Jeong, Joo-Won Lee, Woo Sik Kim, Sung Sik Choe, Kyung-Hee Kim, Ho Seon Park, Hyun Jung Shin, Gha Young Lee, Dongkyu Shin, Hanjae Lee, Jun Hee Lee, Eun Bok Choi, Hyeon Kyu Lee, Heekyoung Chung, Seung Bum Park, Kyong Soo Park, Hyo-Soo Kim, Seonggu Ro, Jae Bum Kim, "A Newly Identified CG301269 Improves Lipid and Glucose Metabolism without Body Weight Gain through Activation of PPAR and PPAR," Diabetes, February, 2011.
Sung Sik Choe, A Hyun Choi, Joo-Won Lee, Kang Ho Kim, Jun-Jae Chung, Jiyoung Park, Kyeong-Min Lee, Keun-Gyu Park, In-Kyu Lee, Jae Bum Kim, "Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells," Diabetes, June, 2007.
Yun S Lee, Woo S Kim, Kang H Kim, Myung J Yoon, Hye J Cho, Yun Shen, Ji-Ming Ye, Chul H Lee, Won K Oh, Chul T Kim, Cordula Hohnen-Behrens, Alison Gosby, Edward W Kraegen, David E James, Jae B Kim, "Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states," Diabetes, August, 2006.
Diabetes Metab J.
Diabetes Res. Clin. Pract .
Endocrinol. Metab.
Endocrinology
Exp. Mol. Med.
Jong Bae Seo, Sung Sik Choe, Hyun Woo Jeong, Sang Wook Park, Hyun Jung Shin, Sun Mi Choi, Jae Young Park, Eun Wook Choi, Jae Bum Kim, Dong Seung Seen, Jae-Yeon Jeong & Tae Gyu Lee, "Anti-obesity effects of Lysimachia foenum-graecum characterized by decreased adipogenesis and regulated lipid metabolism," Exp. Mol. Med., April, 2011.
FASEB J.
Injae Hwang, Yoon Jeong Park, Yeon-Ran Kim, Yo Na Kim, Sojeong Ka, Ho Young Lee, Je Kyung Seong, Yeong-Jae Seok, Jae Bum Kim, "Alteration of gut microbiota by vancomycin and bacitracin improves insulin resistance via glucagon-like peptide 1 in diet-induced obesity," FASEB J., June, 2015.
(** This paper has been highlighted in Nat. Rev. Endo. 11:254 [2015])
FEMS Microbiol. Lett.
Free Radic. Biol. Med.
M A Rashid, Seonmin Lee, Eunyoung Tak, Jisun Lee, Tae Gyu Choi, Joo-Won Lee, Jae Bum Kim, Jang H Youn, Insug Kang, Joohun Ha, Sung Soo Kim, "Carbonyl reductase 1 protects pancreatic β-cells against oxidative stress-induced apoptosis in glucotoxicity and glucolipotoxicity," Free Radic. Biol. Med., November, 2010.
Front. Endocrinol.
Front. Immunol.
Genes Dev.
Jeu Park, Jin Young Huh, Jiyoung Oh, Jong In Kim, Sang Mun Han, Kyung Cheul Shin, Yong Geun Jeon, Sung Sik Choe, Jiyoung Park, and Jae Bum Kim, "Activation of invariant natural killer T cells stimulates adipose tissue remodeling via adipocyte death and birth in obesity.," Genes Dev., November, 2019.
Hanyang Med. Rev.
Hepatology
Jae Ho Lee, Gha Young Lee, Hagoon Jang, Sung Sik Choe, Seung-Hoi Koo, and Jae Bum Kim, "RNF20 regulates hepatic lipid metabolism through PKA-dependent SREBP1c degradation," Hepatology, September, 2014.
(** This paper has been selected as a Highlight paper by the editor and commented in the same issue. Hepatology 60:776-778)
Keun-Gyu Park, Ae-Kyung Min, Eun Hee Koh, Hyoun Sik Kim, Mi-Ok Kim, Hye-Sun Park, Yong-Deuk Kim, Tae-Seung Yoon, Byoung Kuk Jang, Jae Seok Hwang, Jae Bum Kim, Hueng-Sik Choi, Joong-Yeol Park, In-Kyu Lee, Ki-Up Lee, "Alpha-lipoic acid decreases hepatic lipogenesis through AMPK-dependent and –independent pathways," Hepatology, November, 2008.
J Tissue Eng Regen Med.
J. Biol. Chem.
Yun Sok Lee, Jin Woo Choi, Injae Hwang, Joo Won Lee, Jae Ho Lee, A Young Kim, Jin Young Huh, Young Jun Koh, Gou Young Koh, Hee Jung Son, Hiroaki Masuzaki, Kikuko Hotta, Assim A Alfadda, Jae Bum Kim, "Adipocytokine orosomucoid integrates inflammatory and metabolic signals to preserve energy homeostasis by resolving immoderate inflammation," J. Biol. Chem., July, 2010.
Han-Jong Kim, Joon-Young Kim, Ju-Youn Kim, Sang-Kyu Park, Ji-Ho Seo, Jae Bum Kim, In-Kyu Lee, Kyung-Sup Kim, Hueng-Sik Choi, "Differential regulation of human and mouse orphan nuclear receptor small heterodimer partner promoter by sterol regulatory element binding protein-1," J. Biol. Chem., July, 2004.
Jong Bae Seo, Hyang Mi Moon, Mun Ju Noh, Yun Sok Lee, Hyun Woo Jeong, Eung Jae Yoo, Woo Sik Kim, Jiyoung Park, Byung-S Youn, Jae Woo Kim, Sang Dai Park, Jae Bum Kim, "Adipocyte determination- and differentiation-dependent factor 1/sterol regulatory element-binding protein 1c regulates mouse adiponectin expression," J. Biol. Chem., May, 2004.
J. Bone Miner. Res.
J. Cell. Mol. Med.
J. Cell. Physiol.
Karam Dahyaleh, Hye K. Sung, Michelle Prioriello, Palanivel Rengasamy, Nhat H. Lam, Jae B. Kim, Sean Gross, Gary Sweeney, "Iron overload reduces adiponectin receptor expression via a ROS/FOXO1-dependent mechanism leading to adiponectin resistance in skeletal muscle cells," J. Cell. Physiol., January, 2021.
J. Clin. Invest.
Sun-Hye Jeong, Han-Byul Kim, Min-Chul Kim, Ji-Min Lee, Jae Ho Lee, Jeong-Hwan Kim, Jin-Woo Kim, Woong-Yang Park, Seon-Young Kim, Jae Bum Kim, Haeryoung Kim, Jin-Man Kim, Hueng-Sik Choi, Dae-Sik Lim, "Hippo-mediated suppression of IRS2/AKT signaling prevents hepatic steatosis and liver cancer," J. Clin. Invest., March, 2018.
J. Immunol.
Sunmi Han, Heonsik Choi, Myung-gon Ko, Young I. Choi, Dong H. Sohn, Joong K. Kim, Dongho Shin, Heekyoung Chung, Han W. Lee, Jae-B. Kim, Sang D. Park and Rho H. Seong, "Peripheral T cells become sensitive to glucocorticoid- and stress-induced apoptosis in transgenic mice overexpressing SRG3," J. Immunol., July, 2001.
J. Lipid. Res.
Joo-Won Lee, Sung Sik Choe, Hagoon Jang, Jiyeong Kim, Hyun Woo Jeong, Hyunsun Jo, Kyeong-Hoon Jeong, Surendar Tadi, Myoung Gyu Park, Tae Hwan Kwak, Jin Man Kim, Dong-Hoon Hyun, Jae Bum Kim, "AMPK activation with glabridin ameliorates adiposity and lipid dysregulation in obesity," J. Lipid. Res., July, 2012.
J. Mol. Biol.
Mun-Kyoung Kim, Jun Hyuck Lee, Hun Kim, Soo Jeong Park, Sung Hyun Kim, Gil Bu Kang, Yun Sok Lee, Jae Bum Kim, Kyeong Kyu Kim, Se Won Suh, Soo Hyun Eom, "Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866," J. Mol. Biol., September, 2006.
J. Neurochem.
Kor. Diabetes
Kor. J. Endocrinol.
Korean J. Biol. Sci.
Korean J. Genetics
Mass Spectrom. Lett.
Metab. Clin. Exp.
Sadanori Okada 1, Chisayo Kozuka, Hiroaki Masuzaki, Shintaro Yasue, Takako Ishii-Yonemoto, Tomohiro Tanaka, Yuji Yamamoto, Michio Noguchi, Toru Kusakabe, Tsutomu Tomita, Junji Fujikura, Ken Ebihara, Kiminori Hosoda, Hiroshi Sakaue, Hiroyuki Kobori, Mira Ham, Yun Sok Lee, Jae Bum Kim, Yoshihiko Saito, Kazuwa Nakao, "Adipose tissue-specific dysregulation of angiotensinogen by oxidative stress in obesity," Metab. Clin. Exp., September, 2010.
Mol. Cancer Res.
Mol. Cell. Biol.
Jong In Kim, Jeu Park, Yul Ji,a Kyuri Jo, Sang Mun Han, Jee Hyung Sohn, Kyung Cheul Shin, Ji Seul Han, Yong Geun Jeon, Hahn Nahmgoong, Kyung Hee Han, Jiwon Kim, Sun Kim, Sung Sik Choe, Jae Bum Kim, "During adipocyte remodeling, lipid droplet configurations regulate insulin sensitivity through F/G-actin reorganization.," Mol. Cell. Biol., October, 2019.
(** This paper is selected as a “Spotlight” paper. In the same issue (October 2019, Vol 39, Issue 20), Cover Figure has been selected with our data)
Ji Seul Han, Jung Hyun Lee, Jinuk Kong, Yul Ji, Jiwon Kim, Sung Sik Choe, Jae Bum Kim, "Hypoxia Restrains Lipid Utilization via Protein Kinase A and ATGL Downregulation through Hypoxia Inducible Factor.," Mol. Cell. Biol., January, 2019.
(** This paper is selected as a “Spotlight” paper. In the same issue (January 2019, Vol 39, Issue 2), Cover Figure has been selected with our data)
Jae Ho Lee, Yong Geun Jeon, Kyoung-Hwa Lee, Hye Won Lee, Jeu Park, Hagoon Jang, Minyong Kang, Hye Sun Lee, Hee Jin Cho, Do-Hyun Nam, Cheol Kwak, Jae Bum Kim, "RNF20 suppresses tumorigenesis by inhibiting the SREBP1c-PTTG1 axis in kidney cancer.," Mol. Cell. Biol., November, 2017.
(** This paper is selected as a “Spotlight” paper. In the same issue [Nov 2017, Vol 37, Issue 22], cover figure was selected from this paper.)
Jong In Kim, Jin Young Huh, Jee Hyung Sohn, Sung Sik Choe, Yun Sok Lee, Chun Yan Lim, Ala Jo, Seung Bum Park, Weiping Han, Jae Bum Kim, "Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation," Mol. Cell. Biol., May, 2015.
(** This paper is selected as a “Spotlight” paper. In the same issue (May 2015, Vol 35, Issue 10), Cover Figure has been selected with our data.)
Jin Young Huh, Jong In Kim, Yoon Jeong Park, In Jae Hwang, Yun Sok Lee, Jee Hyung Sohn, Sung Kyu Lee, Assim A Alfadda, Su Sung Kim, Sung Hee Choi, Dong-Sup Lee, Se-Ho Park, Rho Hyun Seong, Cheol Soo Choi, Jae Bum Kim, "A Novel Function of Adipocytes in Lipid Antigen Presentation to iNKT Cells," Mol. Cell. Biol., January, 2013.
Sung Soo Chung, Min Kim, Byoung-Soo Youn, Nam Seok Lee, Ji Woo Park, In Kyu Lee, Yun Sok Lee, Jae Bum Kim, Young Min Cho, Hong Kyu Lee, Kyong Soo Park, "Glutathione peroxidase 3 mediates the antioxidant effect of peroxisome proliferators-activated receptor gamma in human skeletal muscle cells," Mol. Cell. Biol., January, 2009.
Jong Bae Seo, Hyang Mi Moon, Woo Sik Kim, Yun Sok Lee, Hyun Woo Jeong, Eung Jae Yoo, Jungyeob Ham, Heonjoong Kang, Myoung-Gyu Park, Knut R Steffensen, Thomas M Stulnig, Jan-Ake Gustafsson, Sang Dai Park, Jae Bum Kim, "Activated liver X receptors stimulate adipocyte differentiation through induction of peroxisome proliferator-activated receptor gamma expression," Mol. Cell. Biol., April, 2004.
L Fajas, K Schoonjans, L Gelman, J B Kim, J Najib, G Martin, J C Fruchart, M Briggs, B M Spiegelman, J Auwerx, "Regulation of peroxisome proliferator-activated receptor gamma expression by adipocyte differentiation and determination factor 1/sterol regulatory element binding protein 1. Implications for adipocyte differentiation and metabolism," Mol. Cell. Biol., August, 1999.
Mol. Cells
Mol. Endocrinol.
A Young Kim, Yun Sok Lee, Kang Ho Kim, Jae Ho Lee, Hee Kyu Lee, Su-Hwa Jang, Seong-Eun Kim, Gha Young Lee, Joo-Won Lee, Sung-Ae Jung, Hee Yong Chung, Sunjoo Jeong, Jae Bum Kim, "Adiponectin Represses Colon Cancer Cell Proliferation via AdipoR1-and R2-mediated AMPK
Activation," Mol. Endocrinol., July, 2010.
Jong Bae Seo, Mun Ju Noh, Eung Jae Yoo, So Yun Park, Jiyoung Park, In Kyu Lee, Sang Dai Park, Jae Bum Kim, "Functional Characterization of the Human Resistin Promoter with Adipocyte Determination- and Differentiation-Dependent Factor 1/Sterol Regulatory Element Binding Protein 1c and CCAAT Enhancer Binding Protein-alpha," Mol. Endocrinol., August, 2003.
Mol. Pharmacol.
Hyun Woo Jeong, Joo-Won Lee, Woo Sik Kim, Sung Sik Choe, Hyun Jung Shin, Gha Young Lee, Dongkyu Shin, Jun Hee Lee, Eun Bok Choi, Hyun Kyu Lee, Gyu Hwan Yon, Bongjun Cho, Hye Ryung Kim, Sung Hee Choi, Young Sun Chung, Seung Bum Park, Heekyoung Chung, Seonggu Ro, Jae Bum Kim, "A Non-TZD PPARα/γ Dualagonist CG301360 Alleviates Insulin Resistance and Lipid Dysregulation in db/db Mice.," Mol. Pharmacol., November, 2010.
Nanotechnology
Nat Commun.
Yong Geun Jeon, Hahn Nahmgoong, Jiyoung Oh, Dabin Lee, Dong Wook Kim, Jane Eunsoo Kim, Ye Young Kim, Yul Ji, Ji Seul Han, Sung Min Kim, Jee Hyung Sohn, Won Taek Lee, Sun Won Kim, Jeu Park, Jin Young Huh, Kyuri Jo, Je-Yoel Cho, Jiyoung Park, Jae Bum Kim*, "Ubiquitin Ligase RNF20 Coordinates Sequential Adipose Thermogenesis with Brown and Beige Fat-Specific Substrates.," Nat Commun., January, 2024.
Sang Mun Han, Eun Seo Park, Jeu Park, Hahn Nahmgoong, Yoon Ha Choi, Jiyoung Oh, Kyung Min Yim, Won Taek Lee, Yun Kyung Lee, Yong Geun Jeon, Kyung Cheul Shin, Jin Young Huh, Sung Hee Choi, Jiyoung Park, Jong Kyoung Kim, Jae Bum Kim*, "Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice.," Nat Commun., December, 2023.
Ji Seul Han, Yong Geun Jeon, Minsik Oh, Gung Lee, Hahn Nahmgoong, Sang Mun Han, Ye Young Kim, Kyung Cheul Shin, Jiwon Kim, Kyuri Jo, Sung Sik Choe, Eun Jung Park, Sun Kim, and Jae Bum Kim, "Adipocyte HIF2α functions as a thermostat via PKA Cα regulation in beige adipocytes," Nat Commun., June, 2022.
(*This paper has been featured in a Nature Communications Editors' Highlights)
Hwan Hee Lee, Seung Min An, Byeong Jin Ye, Jun Ho Lee, Eun Jin Yoo, Gyu Won Jeong, Hyun Je Kang,
Assim A. Alfadda2, Sun Woo Lim, Jiyoung Park, Whaseon Lee-Kwon, Jae Bum Kim,
Soo Youn Choi & Hyug Moo Kwon, "TonEBP/NFAT5 promotes obesity and insulin resistance by epigenetic suppression of white adipose tissue beiging," Nat Commun., July, 2019.
Hagoon Jang, Gha Young Lee, Christopher P. Selby, Gung Lee, Yong Geun Jeon, Jae Ho Lee, Kenneth King Yip Cheng, Paul Titchenell, Morris J. Birnbaum, Aimin Xu, Aziz Sancar & Jae Bum Kim, "SREBP1c-CRY1 signaling represses hepatic glucose production by promoting FOXO1 degradation during refeeding," Nat Commun., July, 2016.
(** This paper was invited from Cell Cycle journal for a Commentary Article.)
A. Young Kim, Yoon Jeong Park, Xuebo Pan, Kyung Cheul Shin, Soo-Heon Kwak, Abdulelah F. Bassas, Reem M. Sallam, Kyong Soo Park, Assim A. Alfadda, Aimin Xu & Jae Bum Kim, "Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance (** This paper has been highlighted in Nat. Rev. Endo. 11:504 [2015])," Nat Commun., July, 2015.
(** This paper has been highlighted in Nat. Rev. Endo. 11:504 [2015])
Mi-Ran Lee, Chae-ji Lim, You-Han Lee, Jong-Gil Park, Seong Keun Sonn, Mi-Ni Lee, In-Hyuk Jung, Se-Jin Jeong, Sejin Jeon, Myoungsook Lee, Ki Sook Oh, Young Yang, Jae Bum Kim, Hueng-Sik Choi, Woojin Jeong, Tae-Sook Jeong, Won Kee Yoon, Hyoung Chin Kim, Jae-Hoon Choi, Goo Taeg Oh, "The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice," Nat Commun., July, 2014.
Nat. Immunol.
Meidi Gu, Xiaofei Zhou, Jee Hyung Sohn, Lele Zhu, Zuliang Jie, Jin-Young Yang, Xiaofeng Zheng, Xiaoping Xie, Jie Yang, Yaoyao Shi, Hans D Brightbill, Jae Bum Kim, Jing Wang, Xuhong Cheng, Shao-Cong Sun, "NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.," Nat. Immunol., February, 2021.
Nat. Metab.
Hwang Chan Yu, Yong Geun Jeon, Ann-Yae Na, Chang Yeob Han, Mi Rin Lee, Jae Do Yang, Hee Chul Yu, Jung Beom Son, Nam Doo Kim, Jae Bum Kim, Sangkyu Lee*, Eun Ju Bae*, Byung-Hyun Park*, "p21-activated kinase 4 counteracts PKA-dependent lipolysis by phosphorylating FABP4 and HSL.," Nat. Metab., January, 2024.
Jeu Park, Do Hoon Lee, Seokjin Ham, Jiyoung Oh, Jung-Ran Noh, Yun Kyung Lee, Yoon Jeong Park, Gung Lee, Sang Mun Han, Ji Seul Han, Ye Young Kim, Yong Geun Jeon, Han Nahmgoong, Kyung Cheul Shin, Sung Min Kim, Sung Hee Choi, Chul-Ho Lee, Jiyoung Park, Tae Young Roh, Sun Kim, Jae Bum Kim., "Targeted erasing of DNA methylation drives adipogenic reprogramming.," Nat. Metab., July, 2022.
Nat. Rev. Endocrinol.
Nucleic Acids Res.
Minkyu Kim, Woojin Lee, Jiyoung Park, Jae Bum Kim, Yeun Kyu Jang, Rho Hyun Seong, Soo Young Choe, Sang Dai Park, "The stress-activated MAP kinase Sty1/Spc1 and a 3'-regulatory element mediate UV-induced expression of uvi15 gene at the post-transcriptional level," Nucleic Acids Res., September, 2000.
Photochem. Photobiol.
PLoS One
Tamara N Dunn, Tasuku Akiyama, Hyun Woo Lee, Jae Bum Kim, Trina A Knotts, Steven R Smith, Dorothy D Sears, Earl Carstens, Sean H Adams, "Evaluation of the synuclein-γ (SNCG) gene as a PPARγ target in murine adipocytes, dorsal root ganglia somatosensory neurons, and human adipose tissue," PLoS One, March, 2015.
Postgrad. Med. J. (BMJ Journals)
PPAR Res.
Trina A Knotts, Hyun Woo Lee, Jae Bum Kim, Pieter J Oort, Ruth McPherson, Robert Dent, Keisuke Tachibana, Takefumi Doi, Songtao Yu, Janardan K Reddy, Kenji Uno, Hideki Katagiri, Magdalena Pasarica, Steven R Smith, Dorothy D Sears, Michel Grino, Sean H Adams, "Molecular Characterization of the Tumor Suppressor Candidate 5 Gene: Regulation by PPAR gamma and Identification of TUSC5 Coding Variants in Lean and Obese Humans," PPAR Res., March, 2010.
Proc. Natl. Acad. Sci.
Yoon Jeong Park, Sangseon Leed, Sangsoo Limd, Hahn Nahmgoong, Yul Ji, Jin Young Huh, Assim A. Alfadda, Sun Kim and Jae Bum Kim, "DNMT1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondrial dynamics," Proc. Natl. Acad. Sci., March, 2021.
(** This paper has been highlighted in the “Commentary” Proc. Natl. Acad. Sci. 2021 118 (15) e2102944118)
Injae Hwang, Kyuri Jo, Kyung Cheul Shin, Jong In Kim, Yul Ji, Yoon Jeong Park, Jeu Park, Yong Geun Jeon, Sojeong Ka, Sujin Suk, Hye Lim Noh, Sung Sik Choe, Assim A. Alfadda, Jason K. Kim, Sun Kim,
and Jae Bum Kim, "GABA-stimulated adipose-derived stem cells suppress subcutaneous adipose inflammation in obesity," Proc. Natl. Acad. Sci., June, 2019.