교수
공영윤 Kong, Young-Yun
연구분야
발달 및 발생생물학
세포생물학
유전학
The Objective of the Laboratory of Development and Disease Modeling is to elucidate disease pathogenesis at the molecular level and identify disease causing genes through mouse genetic studies, loss-of-function; knockout, conditional, knock-in, and gain-of-function; transgenic.
1. Stem cell maintenance & differentiation by microenvironment
2. Tumorigenesis by Notch and Rank signaling
1. Stem cell maintenance & differentiation by microenvironment
2. Tumorigenesis by Notch and Rank signaling
학력/경력
학력
- - 1992.4-1996.3 박사: Kyushu University 의과대학, 일본
- - 1986.3-1988.2 석사: 경희대학교 약학대학 대학원
- - 1982.3-1986.2 학사: 경희대학교 약학대학 약학과
경력
- - 2012 - 현재 교수, 서울대학교 생명과학부
- - 2008 - 2011 부교수, 서울대학교 생명과학부
- - 2006 - 2008 부교수, 포항공과대학교 생명과학과
- - 2000 - 2006 조교수, 포항공과대학교 생명과학과
- - 1997 - 2000 Post-Doc, Amgen Institute, Univ. of Toro
- - 1996 - 1996 Post-Doc, OCI, Univ. of Toronto
주요논문
- Ji-Hoon Kim, Gi-Chan Han, Ji-Yun Seo, Inkuk Park,Wookjin Park, Hyun-Woo Jeong, Su Hyeon Lee, Sung-hwan Bae, Jinwoo Seong,Min-Kyu Yum, Sang-Hyeon Hann, Young-Guen Kwon, Daekwan Seo, Man Ho Choi and Young-Yun Kong (2016). Sex hormones establish a reserve pool of adult muscle stem cells. Nature Cell Biology.
- Min Kyu Yum, Jong-Seol Kang, Al-Eum Lee, Young-Woo Jo, Ji Yun Seo, Hyun-A Kim, Yoon-Young Kim, Jinwoo Seong, Eun Byul Lee, Ji-Hoon Kim, Jung Min Han, Sunghoon Kim, Young-Yun Kong (2016). AIMP2 controls intestinal stem cell compartments and tumorigenesis by modulating Wnt/β-catenin signaling. Cancer res.
- Kim YY, Moon JS, Kwon MC, Shin J, Im SK, Kim HA, Han JK, Kong YY (2014). Meteorin regulates mesendoderm development by enhancing nodal expression. PLoS One, 18;9(2), e88811.
- Shin J, Lee SH, Kwon MC, Yang DK, Seo HR, Kim J, Kim YY, Im SK, Abel ED, Kim KT, Park WJ, Kong YY (2013). Cardiomyocyte specific deletion of crif1 causes mitochondrial cardiomyopathy in mice. PLoS One, 8(1), e53577.
- Hyun-A Kim*, Bon-Kyoung Koo*, Ji-Hoon Cho, Yoon-Young Kim, Jinwoo Seong, Hee Jin Chang, Young-Min Oh, Daniel E. Stange, Jae-Gahb Park, Daehee Hwang and Young-Yun Kong (*Co-first authors) (2012). NOTCH1 counteracts WNT-b-catenin signaling through chromatin modification in colorectal cancer. J Clin Invest, 122(9), 3248-59.