Seoul National University Biological Sciences Website

논문

Laboratory of Innate Immunity and Cell Death

2023

Balamurugan Sundaram, Nagakannan Pandian, Raghvendra Mall, Yaqiu Wang, Roman Sarkar, Hee Jin Kim , R K Subbarao Malireddi, Rajendra Karki, Laura J Janke, Peter Vogel, Thirumala-Devi Kanneganti (2023). "NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs". Cell.

10.1016/j.cell.2023.05.005

Rajendra Karki, Thirumala-Devi Kanneganti (2023). "PANoptosome signaling and therapeutic implications in infection: central role for ZBP1 to activate the inflammasome and PANoptosis". Current opinion in immunology.

10.1016/j.coi.2023.102348

Rajendra Karki, Thirumala-Devi Kanneganti (2023). "ADAR1 and ZBP1 in innate immunity, cell death, and disease". Trends in Immunology.

10.1016/j.it.2023.01.001

Bhesh Raj Sharma, Rajendra Karki, Balamurugan Sundaram, Yaqiu Wang, Peter Vogel, Thirumala-Devi Kanneganti (2023). "The Transcription Factor IRF9 Promotes Colorectal Cancer via Modulating the IL-6/STAT3 Signaling Axis". .

10.3390/cancers14040919

2022

Raghvendra Mall, Ratnakar R Bynigeri, Rajendra Karki, R K Subbarao Malireddi, Bhesh Raj Sharma, Thirumala-Devi Kanneganti (2022). "Pancancer transcriptomic profiling identifies key PANoptosis markers as therapeutic targets for oncology". NAR Cancer.

10.1093/narcan/zcac033

Rajendra Karki, Thirumala-Devi Kanneganti (2022). "Innate immunity, cytokine storm, and inflammatory cell death in COVID-19". Journal of Translational Medicine.

10.1186/s12967-022-03767-z

Yaqiu Wang, Rajendra Karki, Raghvendra Mall, Bhesh Raj Sharma, Ravi C Kalathur, SangJoon Lee, Balabhaskararao Kancharana, Matthew So, Katie L Combs, Thirumala-Devi Kanneganti (2022). "Molecular mechanism of RIPK1 and caspase-8 in homeostatic type I interferon production and regulation". Cell reports.

10.1016/j.celrep.2022.111434

Yaqiu Wang, Nagakannan Pandian, Joo-Hui Han, Balamurugan Sundaram, SangJoon Lee, Rajendra Karki , Clifford S Guy, Thirumala-Devi Kanneganti (2022). "Single cell analysis of PANoptosome cell death complexes through an expansion microscopy method". Cellular and molecular life sciences.

10.1007/s00018-022-04564-z

Rajendra Karki 1, SangJoon Lee 1, Raghvendra Mall 1, Nagakannan Pandian 1, Yaqiu Wang 1, Bhesh Raj Sharma 1, Rk Subbarao Malireddi 1, Dong Yang 2, Sanja Trifkovic 3, Jacob A Steele 4, Jon P Connelly 4, Gella Vishwanath 5, Mitnala Sasikala 6, Duvvur Nageshwar Reddy 7, Peter Vogel 8, Shondra M Pruett-Miller 4, Richard Webby 3, Colleen Beth Jonsson 9, Thirumala-Devi Kanneganti 1 (2022). "ZBP1-dependent inflammatory cell death, PANoptosis, and cytokine storm disrupt IFN therapeutic efficacy during coronavirus infection". Sci Immunol.

10.1126/sciimmunol.abo6294

Balamurugan Sundaram, Rajendra Karki, Thirumala-Devi Kanneganti (2022). "NLRC4 Deficiency Leads to Enhanced Phosphorylation of MLKL and Necroptosis". Immunohorizons actions Search in PubMed Search in NLM Catalog Add to Search ..

10.4049/immunohorizons.2100118

2012

Rajendra Karki 1, Eun-Raye Jeon, Dong-Wook Kim (2012). "Magnoliae Cortex inhibits intimal thickening of carotid artery through modulation of proliferation and migration of vascular smooth muscle cells". Food and Chemical Toxicology.

10.1016/j.fct.2011.11.043

2011

Rajendra Karki 1, Navin Sahi, Eun-Raye Jeon, Yong-Seo Park, Dong-Wook Kim (2011). "Chungtaejeon, a Korean fermented tea, scavenges oxidation and inhibits cytokine induced proliferation and migration of human aortic smooth muscle cells". Plant Foods Hum Nutr.