Seoul National University Biological Sciences Website

Publications

Laboratory of Molecular Genetics

Arch. Biochem. Biophys. (IF:2.935)

Park, S. & GUHUNG JUNG (2002). Hsp90 makes the human HBV Pol competent for in vitro priming rather than maintaining the human HBV Pol/pregenomic RNA complex. Arch. Biochem. Biophys. (IF:2.935), (), .

BBRC (IF:2.466)

Yoon Sik Kim, Hyun Wook Seo, and GUHUNG JUNG (2015). Reactive oxygen species promote heat shock protein 90-mediated HBV capsid assembly. BBRC (IF:2.466), (), .

Eunkyong Ko and GUHUNG JUNG (2014). Positive association of long telomeres with the invasive capacity of hepatocellular carcinoma cells. BBRC (IF:2.466), (), .

Kim, H.S. Jeong, H. Lim, S. & GUHUNG JUNG (2013). Snail inhibits Notch1 intracellular domain mediated transcriptional activation via competing with MAML1. BBRC (IF:2.466), (), .

Lim, S.O. Park, S. Kim, W. Park, S. Kim, H, Kim, Y. Sohn, T. Noh, J. & GUHUNG JUNG (2002). Proteome analysis of hepatocellular carcinoma. BBRC (IF:2.466), (), .

Cho, G. Suh, S.W. & GUHUNG JUNG (IF: 2.484) (2000). HBV Polymerase Interacts Independently with N-Terminal and C-Terminal Fragments of Hsp90. BBRC (IF:2.466), (), .

Cho, G. Park, S. & GUHUNG JUNG (IF: 2.484) (2000). Localization of HSP90 Binding Sites in the Human Hepatitis B Virus Polymerase. BBRC (IF:2.466), (), .

Lee, Y.I. Hong, Y.B. Kim, Y. Rho, H.M. & GUHUNG JUNG (1997). RNase H Activity of Human Hepatitis B Virus Polymerase Expressed in E. coli. BBRC (IF:2.466), (), .

Lee, N. Hwang, M. GUHUNG JUNG Kim, Y. & Min, K. (1996). Physical Structure and Expression of alk BA Encoding Alkane Hydroxylase and Rubred-oxin Reductase from Pseudomonas maltophilia. BBRC (IF:2.466), (), .

Jeong, J.H. Kwak, D.S. Rho, H.M. & GUHUNG JUNG (1996). The Catalytic Properties of Human Hepatitis B Virus Polymerase. BBRC (IF:2.466), (), .

Kim, H.T. Kim, Y.H. Nam, J.H. Lee, H.J. Rho, H.M. GUHUNG JUNG (1994). Study of 5’-flanking region of human Cu/Zn superoxide dismutase. BBRC (IF:2.466), (), .

GUHUNG JUNG Leavitt, M.C. Schultz, M & Ito, J. (1990). Site-specific mutagenesis of PRD1 DNA polymerase : Mutation in highly conserved region of the family B DNA polymerase. BBRC (IF:2.466), (), .

BBRC (IF:2.559)

Hyun-Wook Seo, Joon Pyung Seo, and GUHUNG JUNG (2018). Heat shock protein 70 and heat shock protein 90 synergistically increase hepatitis B viral capsid assembly. BBRC (IF:2.559), (), .

Biochemical Journal (IF:3.797)

Kang, H. Yu, J. & GUHUNG JUNG (2008). Phosphorylation of hepatitis B virus core C-terminally truncated protein(Cp 149) by PKC increases capsid assembly and stability. Biochemical Journal (IF:3.797), (), .

Kang, H.Y. Lee, S. Park, S.G. Yu, J. Kim, Y. & GUHUNG JUNG (2006). Phosphorylation of hepatitis B virus core protein at Ser87 facilitates core assembly. Biochemical Journal (IF:3.797), (), .

Biochemistry and Molecular Biology International (IF:4.907)

Kim, Y. Hong, Y.B. & GUHUNG JUNG (1999). Hepatitis B Virus : DNA Polymerase Activity of Delection Mutants. Biochemistry and Molecular Biology International (IF:4.907), (), .

Cho, G. Kang, S. Seo, S.J. Kim, Y. & GUHUNG JUNG (1997). The Transcriptional Repression of the Human Gu/Zu Superoxide Dismutase(sod1) Gene by the Anticancer Drug, Nitomycin C(mmc). Biochemistry and Molecular Biology International (IF:4.907), (), .

Biochim. Biophys. Acta (IF:4.66)

Lee, S.H. Park, S.G. Lim, S.O. & GUHUNG JUNG (2005). The hepatitis B virus X protein up-regulates lymphotoxin a expression in hepatocytes. Biochim. Biophys. Acta (IF:4.66), (), .

Zhu, W. Leavitt, M.C. GUHUNG JUNG & Ito, J. (1994). Mutagenesis of a highly conserved lys340 of the PRD1 DNA polymerase. Biochim. Biophys. Acta (IF:4.66), (), .

Biotechnology Letters (IF:1.73)

Han-Joo Lee, Yong-tae Kwon, Hyun-mo Rho & GUHUNG JUNG (1993). Expression of Hepatitis B virus polymerase Gene in E-coli. Biotechnology Letters (IF:1.73), (), .

BMC Biology (IF:6.779)

Lim, S. Kim, H.S. Quan, X. Ahn, S. Kim, H., Hsieh, D. Seong, J.K. & GUHUNG JUNG (2011). Notch1 binds and induces degradation of Snail in hepatocellular carcinoma. BMC Biology (IF:6.779), (), .

Cancer letters (IF:6.375)

Antony Hsieh, Hyeon-Seop Kim, Seung-Oe Lim, Dae-Yeul Yu, GUHUNG JUNG (2011). Hepatitis B viral X protein interacts with tumor suppressor adenomatous polyposis coli to activate Wnt/b-catenin signaling. Cancer letters (IF:6.375), (), .

Park, S.G. Min, J.Y. Chung, C. Hsieh, A. & GUHUNG JUNG (2009). Tumor suppressor protein p53 induces degradation of the oncogenic protein HBx. Cancer letters (IF:6.375), (), .

Cancer Science (IF:3.974)

Chung, C. Park, S.G. Park, Y.M., Joh, J.W. & GUHUNG JUNG (2007). Interferon-gamma sensitizes hepatitis B virus-expressing hepatocarcinoma cells to 5-fluorouracil through inhibition of hepatitis B virus-mediated nuclear factor-kappaB activation. Cancer Science (IF:3.974), (), .

Clinical Cancer Research (IF:9.619)

Kim, W. Lim, S.O. Kim, J. Ryu, Y.H. Byeon, J. Kim, H. Kim, Y. Heo, J.S. Park, Y.M. & GUHUNG JUNG (2003). Comparison of Proteome between Hepatitis B Virus- and Hepatitis C Virus- associated Hepatocellular Carcinoma. Clinical Cancer Research (IF:9.619), (), .

Current Microbiology (IF:1.322)

Yoo, H. GUHUNG JUNG & Rho, H.M. (1995). Transcriptional Control of saccaromyces cervisiae ADH1 Gene by Autonomously Replicating sequence binding Factor 1. Current Microbiology (IF:1.322), (), .

European Journal of Biochemistry (IF:3.579)

Park, S.G. Kim, Y. Park, E. Ryu, H.M. & GUHUNG JUNG (2003). Fidelity of Hepatitis B Virus Polymerase. European Journal of Biochemistry (IF:3.579), (), .

FEBS journal (IF:3.902)

Gu, J. Lim, S. Park, Y.M. & GUHUNG JUNG (2008). A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion. FEBS journal (IF:3.902), (), .

FEBS Letters (IF:3.623)

Hyeon Seop Kim and GUHUNG JUNG (2014). Reactive oxygen species increase HEPN1 expression via activation of the XBP1 transcription factor. FEBS Letters (IF:3.623), (), .

Heewon Jeong, Min-Hyung Cho, and GUHUNG JUNG (2014). Interaction between nucleophosmin and HBV core protein increases HBV capsid assembly. FEBS Letters (IF:3.623), (), .

Quan, X. Lim, S. & GUHUNG JUNG (2011). Reactive oxygen species downregulate catalase expression via methylation of a CpG Island in the Oct-1 promoter. FEBS Letters (IF:3.623), (), .

Min, J.Y. Lim, S. & GUHUNG JUNG (2010). Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter. FEBS Letters (IF:3.623), (), .

Lim, S. Kim, H. & GUHUNG JUNG (2010). p53 inhibits tumor cell invasion via the degradation of snail protein in hepatocellular carcinoma. FEBS Letters (IF:3.623), (), .

Kim, H.R. Lee, S.H. & GUHUNG JUNG (2009). The hepatitis B viral X protein activates NF-κB signaling pathway through the up-regulation of TBK1. FEBS Letters (IF:3.623), (), .

Park, S.G. Lee, T. Kang, H.Y. Park, K. Cho, K. & GUHUNG JUNG (2006). The Influence of the Signal Dynamics of Activated Form of IKK on NF-κB and Anti-apoptotic Gene Expressions: A Systems Biology Approach. FEBS Letters (IF:3.623), (), .

Kim, Y.H. Yoo, H.Y. Chang, M.S. GUHUNG JUNG & Rho, H.M. (1997). C/EBPα is a major activator for the transcription of rat Cu/Zn superoxide dismutase gene in liver cell. FEBS Letters (IF:3.623), (), .

Free Radical Research (IF:3.188)

Hyeon Seop Kim, and GUHUNG JUNG (2014). Notch1 increases Snail expression under high reactive oxygen species conditions in hepatocellular carcinoma cells. Free Radical Research (IF:3.188), (), .

Gastroenterology (IF:18.392)

Lim, S.O. Gu, J. Kim, M.S. Kim, H. Park, Y.N. Park, S.K. Cho, J.W. Park, Y.M. & GUHUNG JUNG (2008). Epigenetic Changes induced by reactive oxygen species in Hepatocellular Carcinoma: Methylation of the E-cadherin Promoter. Gastroenterology (IF:18.392), (), .

Park, S.G. Ryu, H.M. Lim, S.O. Kim, Y. Hwang, S.B. & GUHUNG JUNG (2005). Interferon-γ Inhibits Hepatitis B Virus-Induced NF-κB Activation through Nuclear Localization of NF-κB-inducing Kinase. Gastroenterology (IF:18.392), (), .

Gene (IF:2.415)

Seo, S.J. Kang, S.S. Cho, G. Rho, H.M. & GUHUNG JUNG (1997). C/EBPα and C/EBPβ play similar roles in the transcription of the human Cu/Zu Gene. Gene (IF:2.415), (), .

Seo, S.J. Kim, H.T. Cho, G. Rho, H.M. & GUHUNG JUNG (1996). Sp1 and C/EBP-regulated factor regulate the transcription of human Cu/Zu SOD gene. Gene (IF:2.415), (), .

Yong-ho Kim, GUHUNG JUNG, Ji-young Kim & Hyun-mo Rho (1993). Isolation and analysis of the Cu/Zu superoxide dismutase. Gene (IF:2.415), (), .

Hepatology (IF:13.246)

Eunkyong Ko, Hyun-Wook Seo, Eun Sun Jung, Soomi Ju, Baek-hui Kim, Hyeki Cho, Yoon Jun Kim, Young Min Park, Jong-Seo Kim, and GUHUNG JUNG (2018). PI3Kδ is a new therapeutic target in hepatocellular carcinoma. Hepatology (IF:13.246), (), .

Eunkyong Ko, Jong-Seo Kim, Soomi Ju, Hyun-Wook Seo, Yeonji Chang, Jung-Ah Kang, Sung- Gyoo Park, and GUHUNG JUNG (2018). Oxidatively modified PDIA3 promotes DKC1‐mediated malignancy and survival of hepatocellular carcinoma cells. Hepatology (IF:13.246), (), .

Eunkyong Ko, Hyun-Wook Seo, GUHUNG JUNG (2017). Telomere length and ROS levels are positively associated with a high risk of mortality and recurrence in hepatocellular carcinoma.. Hepatology (IF:13.246), (), .

Eunkyong Ko, Eun Sun Jung, and GUHUNG JUNG (2016). Telomerase Reverse Transcriptase Promoter Methylation Is Related to a Risk of Recurrence in Hepatocellular Carcinoma. Hepatology (IF:13.246), (), .

Lim, S. Park, Y.M. Kim, H.S. Quan, X. Yoo, J.E. Park, Y.N. Choi, G.H. & GUHUNG JUNG (2011). Notch1 Differentially Regulates Oncogenesis by Wildtype p53 Overexpression and p53 Mutation in Grade III Hepatocellular Carcinoma. Hepatology (IF:13.246), (), .

J. Enz. Inhib. Med. Chem. (IF:1.618)

Cho, M. Song, J. Kim, H. Park, S. & GUHUNG JUNG (2013). Structure-based design and biochemical evaluation of sulfanilamide derivatives as hepatitis B virus capsid assembly inhibitors. J. Enz. Inhib. Med. Chem. (IF:1.618), (), .

Jounal of Biochemistry

Chun, J. Kwon, T. Kim, D.J. Park, I. GUHUNG JUNG Lee, E.J. Hong, S.K. Chang, S. Kim, H.Y. & Kang, S.S. (2003). Inhibition of Mitogen-Activated Kinase Kinase Kinase 3 Activity through Phosphorylation by the Serum- and Glucocorticoid-Induced Kinase 1. Jounal of Biochemistry, (), .

Journal of Biological Chemistry (IF: 4.773)

Park, S.G. Chung, C. Kang, H. Kim, J. & GUHUNG JUNG (2006). Up- regulation of Cyclin D1 by HBx is mediated by NF-kB2/Bcl3 complex through kB site of Cyclin D1 promoter. Journal of Biological Chemistry (IF: 4.773), (), .

Journal of Biological Chemistry (IF:4.773)

Park, S.G. Lee, S.M. & GUHUNG JUNG (2003). Antisense Oligodeoxynucleotides Targeted against Molecular Chaperonin Hsp60 Block HBV Replication. Journal of Biological Chemistry (IF:4.773), (), .

Journal of Hepatology (IF:12.486)

Park, C. Choi, S. Kang, S. Kang, J. Ahn, B. Kim, H., GUHUNG JUNG, Choi, K. & Hwang, S.B. (2009). Nonstructural 5A protein activates b-catenin signaling cascades: Implication of hepatitis C virus-induced liver pathogenesis. Journal of Hepatology (IF:12.486), (), .

Journal of International Society of Life Information Science

Sung, B. Ogay, V. Yoo, J.S. Yu, H.S. Lee, B. Chung, C. GUHUNG JUNG & Soh, K. (2005). UV-A-Induced Activation of Bonghan Granules in Motion. Journal of International Society of Life Information Science, (), .

Journal of Viral Hepatitis (IF:4.122)

Cho, M.H., Jeong, H., Kim, Y.S., Kim, J., & GUHUNG JUNG (2014). 2-Amino-N-(2,6-dichloropyridin-3-yl)acetamide derivatives as a novel class of HBV capsid assembly inhibitor. Journal of Viral Hepatitis (IF:4.122), (), .

Journal of Virology (IF:4.663)

Park, S. & GUHUNG JUNG (2001). Human Hepatitis B Virus Polymerase Interacts with the Molecular Chaperonin Hsp60. Journal of Virology (IF:4.663), (), .

Life Science (IF:2.936)

Woo, D.H. Han, I. & GUHUNG JUNG (2004). Mefenamic acid-induced apoptosis in human liver cancer cell-lines through caspase-3 pathway. Life Science (IF:2.936), (), .

Molecular and Cellular Biology (IF:4.398)

Choi, S. Park, K. Ahn, B. GUHUNG JUNG Lai, M.M.C. & Hwang, S.B. (2006). Hepatitis C virus nonstructural 5B protein regulates TNF-α signaling through effects on cellular IκB kinase. Molecular and Cellular Biology (IF:4.398), (), .

Nucleic Acids Res.

Hsieh, J. GUHUNG JUNG Leavitt, M.C. & Ito, J. (1987). Primary structure of the DNA terminal protein of bacteriophage PRD1. Nucleic Acids Res., (), .

GUHUNG JUNG Leavitt, M.C. & Ito, J. (1987). Yeast Killer plasmid pGKL1 encoded a DNA polymerase belong to a family B DNA polymerase. Nucleic Acids Res., (), .

Nucleic Acids Research (IF:10.162)

Cho, G. & GUHUNG JUNG (1995). Structure-function analysis of the DNA binding domain of Saccharomyces cerevisiae ABF1. Nucleic Acids Research (IF:10.162), (), .

Oncotarget (IF:5.168)

Eunkyong Ko, Hyun-Wook Seo, Eun Sun Jung, Baek-hui Kim, GUHUNG JUNG (2016). The TERT promoter SNP rs2853669 decreases E2F1 transcription factor binding and increases mortality and recurrence risks in liver cancer. Oncotarget (IF:5.168), (), .

Physiologia Plantarum (IF:3.33)

Yoo, J. & GUHUNG JUNG (1995). DNA uptake by imbibition and expression of a foreign gene in rice. Physiologia Plantarum (IF:3.33), (), .

PNAS (IF:9.661)

Jung-Ah Kang, Sang-Heon Park, Sang Phil Jeong, Min-Hee Han, Cho-Rong Lee, Kwang Min Lee, Namhee Kim, Mi-Ryoung Song, Murim Choi, Michael Ye, Guhung Jung, Won-Woo Lee, Soo Hyun Eom, Chul-Seung Park, and Sung-Gyoo Park (2016). Epigenetic regulation of Kcna3-encoding Kv1.3 potassium channel by cereblon contributes to regulation of CD4+ T-cell activation. PNAS (IF:9.661), (), .

GUHUNG JUNG Leavitt, M.C. Hsieh, J. & Ito, J (1988). Bacteriophage PRD1 DNA polymerase: Evolution of DNA polymerase. PNAS (IF:9.661), (), .

Proteins

Lee, H.H. Kim, H.S. Kang, J.Y. Lee, B.I. Ha, J.Y. Yoon, H.J. Lim, S.O. GUHUNG JUNG & Suh, S.W. (2007). Crystal structure of human nucleophosmin-core reveals plasticity of the pentamer-pentamer interface. Proteins, (), .

Proteomics (IF:4.041)

Park, S.G. Yoo, W.G. Song, J.S. Jung, H.S. Kim, C.J. Oh, S.Y. Yoon, B.H. GUHUNG JUNG Kim, H.J. & Nirasawa, T. (2006). Proteome analysis of human amnion and amniotic fluid by two-dimensional electrophoresis and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Proteomics (IF:4.041), (), .

Redox biology

Eunkyong Ko, Jong-Seo Kim, Jong Woo Bae, Jeesoo Kim, Sung-Gyoo Park, and Guhung Jung* (2019). SERPINA3 is a key modulator of HNRNP-K transcriptional activity against oxidative stress in HCC. Redox biology, (), .

Virology (IF:3.353)

Shim, H.Y. Quan, X. Yi, Y. & GUHUNG JUNG (2011). Heat shock protein 90 facilitates formation of the HBV capsid via interacting with the HBV core protein dimers. Virology (IF:3.353), (), .

Choi, Y. Park, S.G. Yoo, J. & GUHUNG JUNG (2005). Calcium ions affect the hepatitis B virus core assembly. Virology (IF:3.353), (), .

Park, S. Lim, S.O. & GUHUNG JUNG (2002). Binding Site Analysis of Human HBV Pol for Molecular Chaperonin, Hsp60. Virology (IF:3.353), (), .

Virus genes (IF:1.431)

Lee, S.M. Park, S.G. Park, E. Lee, J.Y. & GUHUNG JUNG (2003). The 113th and 117th charged amino acids in the 5th alpha-helix of the HBV core protein are necessary for pgRNA encapsidation. Virus genes (IF:1.431), (), .

Yoo, J. & GUHUNG JUNG (2002). Hepatitis B Virus Carries a Foreign Gene into Liver Cells in Vitro. Virus Genes (IF:1.431), (), .

Kim, Y. & GUHUNG JUNG (1999). Active human hepatitis B viral polymerase expressed in rabbit reticulocyte lysate system. Virus genes (IF:1.431), (), .

Virus research (IF:2.484)

Hyun Wook Seo, Joon Pyung Seo, Yuri Cho, Eunkyong Ko, Yoon Jun Kim and GUHUNG JUNG (2019). Cetylpyridinium chloride interaction with the Hepatitis B virus core protein inhibits capsid assembly. Virus research (IF:2.484), (), .

Virus Research (IF:2.628)

Gu, J. Lim, S.O. Oh, S.J. Yoon, S. Seong, J. & GUHUNG JUNG (2008). HBx modulates iron regulatory protein 1-mediated iron metabolism via reactive oxygen species. Virus Research (IF:2.628), (), .

World Journal of Gastroenterology (IF:3.365)

Ryu, H.M. Park, S.G. Yea, S.S. Jang, W.H. Yang, W. & GUHUNG JUNG (2006). Gene Expression Analysis of Primary Normal Human Hepatocytes infected by Human Hepatitis B Virus. World Journal of Gastroenterology (IF:3.365), (), .

Lim, S.O. Park, S.G. Yoo, J. Park, Y.M. Kim, H. Jang, K. Cho, J.W. Yoo, B.C. Park, C.K. & GUHUNG JUNG (2005). Expression of Heat Shock Proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in Hepatitis B Virus-Related Hepatocellular Carcinomas and Dysplastic Nodules. World Journal of Gastroenterology (IF:3.365), (), .