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김재범

Professor

Kim, Jae Bum 김재범

  • Major : Adipocyte and Metabolism
  • Lab. : Laboratory of Adipocyte and Metabolism Research
  • Office : 105-333
  • Office Phone : +82-2-880-5852
  • Lab Phone : +82-2-880-4409
  • Website : http://biosci.snu.ac.kr/lamr
  • Email : jaebkim@snu.ac.kr

김재범
Research
Cell Biology Genetics Molecular Biology
1. Mechanism of Adipocyte Differentiation
2. Gene Expression Regulation of Lipogenesis and Insulin-dependent Genes
3. Molecular Mechanisms for Obesity and Diabetes
Education/Carrer
Education
  • - 1984 - 1988 B.S. Dept. of Zoology, Seoul National University
  • - 1988 - 1990 M.A. Cell & Molecular Biology, Seoul National University
  • - 1991 - 1996 Ph.D. Dept. of Microbiology & Molecular Genetics, Harvard University, U.S.A
Career
  • - 1996- 1997 Postdoctoral Fellow. Dana-Farber Cancer Inst., Harvard Medical School, U.S.A.
  • - 1997 - 2000 Postdoctoral Fellow. Cancer Research Center, Massachusetts Institute of Technology, U.S.A.
  • - 2000 - Present Assistant Professor, Associate Professor, Professor, School of Biological Sciences, Seoul National University
  • - 2004 - Present Associate Member of Korean Academy of Science and Technology
  • - 2005 - 2008 Member of National Bioethics Evaluation, Ministry of Health & Welfare
  • - 2007 - 2008 Visiting Professor, Dept. of Medicine, Univ. of California, San Diego, U.S.A.
  • - 2009 - 2011 Director, Institute of Laboratory Animal Research, Seoul National University, Seoul, Korea
  • - 2011 - 2012 Director, Institute of Molecular Biology and Genetics, Seoul National University, Seoul, Korea
  • - 2011 - 2020 Director, Center for Adipose Tissue Remodeling, Creative Research Initiatives
  • - 2013 -2014 Member of Presidential Advisory Council on Science & Technology
  • - 2014 - 2015 Visiting Professor/ Project Scientist, Dept. of Pathology, Univ. of California, Los Angeles, U.S.A
  • - 2020 - Present Director, Center for Studies on Structure-Function in Adipocyte
  • - 2021 - 2023 Editor-in-Chief, Molecules and Cells
  • - 2021 - 2023 Chair of School of Biological Sciences, Seoul National University, Seoul, Korea
Publications
  1. J. Kong, Y. Ji, Y. G. Jeon, J. S. Han, K. H. Han, J. H. Lee, G. Lee, H. Jang, S. S. Choe, M. Baes, and J. B. Kim*. Spatiotemporal contact between peroxisome and lipid droplet regulates fasting-induced lipolysis via PEX5. Nat Commun., 11(1):578, 2020. 01.
  2. Y. J. Park, S. Lee, S. Lim, H. Nahmgoong, Y. Ji, J. Y. Huh, A. A. Alfadda, S. Kim, and J. B. Kim*. Dnmt1 maintains metabolic fitness of adipocytes through acting as an epigenetic safeguard of mitochondria dynamics. Proc. Natl. Acad. Sci., 118(11): e2021073118, 2021. 03. (This paper is highlighted in the ‘Commentary’ in Proc. Natl. Acad. Sci. 2021 118 (15) e2102944118)
  3. J. H. Sohn, Y. Ji, C. Cho, H. Nahmgoong, S. Lim, Y. G. Jeon, S. M. Han, J. S. Park, I. Rhee, H. Kim, S. Kim, and J. B. Kim*. Spatial regulation of reactive oxygen species via G6PD in nrown adipocytes Supports thermogenic function. Diabetes, 70:22756-70, 2021. 12. (In the same issue, cover figure is selected from this paper.)
  4. H. Nahmgoong, Y. G. Jeon, E. S. Park, Y. H. Choi, S. M. Han, J. Park, Y. Ji, J. H. Sohn, J. S. Han, Y. Y. Kim, I. J. Hwang, Y. K. Lee, J. Y. Huh, S. S. Choe, T. J. Oh, S. H. Choi, J. K. Kim, and J. B. Kim*. Distinct properties of adipose stem cell subpopulations determine fat depot-specific characteristics. Cell Metab., 34:458-472, 2022. 03. (This study is highlighted on the cover figure. This paper is highlighted in Nat. Rev. Endocrinol. 18:133 [2022])
  5. G. Lee, Y. Y. Kim, H. Jang, J. S. Han, H. Nahmgoong, Y. J. Park, S. M. Han, C. Cho, S. Lim, J. Noh, W. K. Oh, C. Lee, S. Kim, and J. B. Kim*. SREBP1c-PARP1 axis tunes anti-senescence activity of adipocytes and ameliorates metabolic imbalance in obesity. Cell Metab., 34:702-718, 2022. 05. (This paper is introduced as ‘research highlights’ in Nat. Cell Biol. 24:601 [2022])
  6. J. S. Han, Y. G. Jeon, M. Oh, G. Lee, H. Nahmgoong, S. M. Han, Y. Y. Kim, K. C. Shin, J. Kim, K. Jo, S. S. Choe, E. J. Park, S. Kim, and J. B. Kim*. Adipocyte HIF2alpha functions as a thermostat via PKA Cα regulation in beige adipocytes. Nat. Commun., 13:3268, 2022. 06.
  7. J. Park, D. H. Lee, S. Ham, J. Oh, J. Noh, Y. K. Lee, Y. J. Park, G. Lee, S. M. Han, J. S. Han, Y. Y. Kim, Y. G. Jeon, H. Nahmgoong, K. C. Shin, S. M. Kim, S. H. Choi, C. Lee, J. Park, T. Y. Roh, S. Kim, and J. B. Kim*. Targeted erasing of DNA methylation drives adipogenic reprogramming. Nat. Metab., 4(7):918-931, 2022.07.
  8. Y. G. Jeon, Y. Y. Kim, G. Lee, J. B. Kim*. Physiological and pathological roles of lipogenesis. Nat. Metab., 5:735-759, 2023.05
  9. S. M. Han, E. S. Park, J. Park, H. Nahmgoong, Y. H. Choi, J. Oh, K. M. Yim, W. T. Lee, Y. G. Jeon, K. C. Shin, J. Y. Huh, S. H. Choi, J. Park, J. K. Kim, and J. B. Kim*. Unique adipose tissue invariant natural killer T cell subpopulations control adipocyte turnover in mice. Nat. Commun. 14:8512, 2023.12.
  10. Y. G. Jeon, H. Nahmgoong, J. Oh, D. Lee, D. W. Kim, J. E. Kim, Y. Y. Kim, Y. Ji, J. S. Han, S. M. Kim, J. H. Sohn, W. T. Lee, S. W. Kim, J. Park, J. Y. Huh, K. Jo, J-Y Cho, J. Park, and J. B. Kim*. Ubiquitin Ligase RNF20 Coordinates Sequential Adipose Thermogenesis with Brown and Beige Fat-Specific Substrates. Nat. Commun, 15:940, 2024.01.
Laboratory of Adipocyte and Metabolism Research, Bldg105(W)-Rm.333, Seoul National University. 1 Gwanak-ro, Gwanak-gu, Seoul 08826
jaebkim@snu.ac.kr · 02-880-4409
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