Research in my lab focuses on the molecular mechanisms leading to the emergence of the chronic inflammatory responses to infection and cellular stress and how they are linked to homeostasis as well as disease. We are also interested in studying virus-host interactions using HCMV and HIV as primary models.
Ongoing research projects include:
● Inflammatory response to the cellular accumulation of misfolded or immatured metabolites (proteins, RNA, DNA)
● Biochemical, molecular as well as functional studies of signaling molecules involved in the sensing and killing of bacteria and viruses
● Host & virus interaction (RNA regulation in viruses and immune systems)
● Molecular mechanisms for SAMHD1 action in HIV-1 restriction and nucleic acid-mediated immune responses
