While I was preparing the lecture for my Membrane Biology class, I happen to bump into the interview of Rod MacKinnon and Peter Agre for the Nobel Prize in Chemistry in 2003.  They got the prize for discoveries of the channels in the membrane.

http://nobelprize.org/mediaplayer/index.php?id=551

They talk about what it is like to be a scientist; how a discovery is made (1:55); the discovery of the channels (6:10); how details are important in science (15:33); the relation between science and society (19:06); the responsibility of scientists (21:30); and the joy of working in a laboratory (27:00).

I highly recommend you to listen to their interview.  It’s inspiring and fun!