Han-Byul Kim, Sangjin Yoo, Hoyun Kwak, Shi-Xun Ma, Ryunhee Kim, Minhyeok Lee, Nui Ha, Soonil Pyo, Soon-Gu Kwon, Eun-Ho Cho, Sang-Myeong Lee, Juwon Jang, Won Kyum Kim, Hae-Chul Park, Minkyung Baek, Yosub Park, Ji-Young Park, Jin-Woo Park, Sun Wook Hwang, Jong-Ik Hwang, Jae Young Seong (2025). Inhibition of FAM19A5 reverses synaptic loss and cognitive decline in mouse models of Alzheimer’s disease. Alzheimer's Research & Therapy, 17(1), 168.
Meghana Kshirsagar*, Artur Meller, Ian R. Humphreys, Samuel Sledzieski, Yixi Xu, Rahul Dodhia, Eric Horvitz, Bonnie Berger, Gregory R. Bowman, Juan Lavista Ferres, David Baker, Minkyung Baek* (2025). Rapid and accurate prediction of protein homo-oligomer symmetry using Seq2Symm. Nature Communications, (), .
*Co-corresponding authors
Ian R. Humphreys#, Jing Zhang#, Minkyung Baek#,*, Yaxi Wang#, Aditya Krishnakumar, Jimin Pei, Ivan Anishchenko, Catherine A. Tower, Blake A. Jackson, Thulasi Warrier, Deborah T. Hung, S. Brook Peterson, Joseph D. Mougous, Qian Cong*, David Baker* (2024). Protein interactions in human pathogens revealed through deep learning. Nature Microbiology, 9(), 2642–2652.
#co-first authors, *co-corresponding authors
Joseph L Watson, David Juergens, Nathaniel R Bennett, Brian L Trippe, Jason Yim, Helen E Eisenach, Woody Ahern, Andrew J Borst, Robert J Ragotte, Lukas F Milles, Basile IM Wicky, Nikita Hanikel, Samuel J Pellock, Alexis Courbet, William Sheffler, Jue Wang, Preetham Venkatesh, Isaac Sappington, Susana Vázquez Torres, Anna Lauko, Valentin De Bortoli, Emile Mathieu, Sergey Ovchinnikov, Regina Barzilay, Tommi S Jaakkola, Frank DiMaio,Minkyung Baek, David Baker (2023). De novo design of protein structure and function with RFdiffusion. Nature, 620(7976), 1089–1100.
Nathaniel R Bennett, Brian Coventry, Inna Goreshnik, Buwei Huang, Aza Allen, Dionne Vafeados, Ying Po Peng, Justas Dauparas, Minkyung Baek, Lance Stewart, Frank DiMaio, Steven De Munck, Savvas N Savvides, David Baker (2023). Improving de novo protein binder design with deep learning. Nature Communications, 14(1), 2625.
Mark R MacRae, Dhenesh Puvanendran, Max AB Haase, Nicolas Coudray, Ljuvica Kolich, Cherry Lam, Minkyung Baek, Gira Bhabha, Damian C Ekiert (2023). Protein-protein interactions in the Mla lipid transport system probed by computational structure prediction and deep mutational scanning. Journal of Biological Chemistry, 299(6), 104744.