백대현

조교수

백대현 Baek, Daehyun

백대현
연구분야
생물정보학 유전체학

Computational Biology and Bioinformatics 
- Large-scale sequence analysis 
- Bio big data: genome, transcriptome, and proteome
 

Noncoding Genome

- MicroRNA targeting and biogenesis
- Other non-coding RNAs
- RNA-binding proteins
- Alternative mRNA splicing and alternative promoters

 

Cancer Genomics
- Whole exome and genome analysis
- Development of cancer genome analysis software

학력/경력
학력
  • - 2000-2007 Ph.D. in Bioengineering at University of Washington (Advisor: Phil Green)
  • - 1993-1999 B.S. in Electrical Engineering at KAIST (Minor in Biological Sciences)
  • - 1991-1993 Seoul Science High School
경력
  • - 2010-Present Assistant Professor of School of Biological Sciences at SNU
  • - 2007-2010 Postdoctoral Fellow at Whitehead Institute / MIT / HHMI (Advisor: David Bartel)
주요논문
  1. D. Kim*, Y. M. Sung*, J. Park*, S. Kim, J. Kim, J. Park, H. Ha, J. Y. Bae, S. Kim, and D. Baek, General Rules for Functional MicroRNA Targeting, Nature Genetics, 2016
  2. S. Choi*, H. R. Kim*, C. O. Sung*, ..., G. Kong#, D. Baek#, and S. J. Jang#, Genomic Alterations in the RB Pathway Indicate Prognostic Outcomes of Early-Stage Lung Adenocarcinoma, Clinical Cancer Research, 2015
  3. D. Garcia*, D. Baek*#, C. Shin, G. Bell, A. Grimson, and D. Bartel#, Weak Seed-Pairing Stability and High Target-Site Abundance Decrease the Proficiency of lsy-6 and Other miRNAs, Nature Structural and Molecular Biology, 2011.
  4. D. Baek*, J. Villen*, C. Shin*, F. Camargo, S. Gygi, and D. Bartel, The Impact of MicroRNAs on Protein Output, Nature, 2008.
  5. D. Baek#, C. Davis, B. Ewing, D. Gordon, and P. Green#, Characterization and Predictive Discovery of Evolutionarily Conserved Mammalian Alternative Promoters, Genome Research, 2007.
  6. D. Baek# and P. Green#, Sequence Conservation, Relative Isoform Frequencies, and Nonsense-Mediated Decay in Evolutionarily Conserved Alternative Splicing, Proceedings of the National Academy of Sciences U.S.A., 2005.
    (*co-first authors, #co-corresponding authors)