2014.04.08. Journal and patent trends by OH! team

천지녕l 2014-04-15l Hit 1102

Keywords
•Cytochrome P450 (CYPs)
•Brassinosteroid
•Plant hormone
•Steroid hydroxylase
•Herbicide resistance
•Natural product: Triterpenoid
Patent Trend
•Herbicide related CYPs
–사플루페나실 –resistence plant: OsCYP72A15
•Brassinosteroid
–BAS (CYP72B1)
–BIA (Brassinoteroid inactivator): Acyltransferase
–CYP85A2
–DDWF1 (AF218296)
–pFGC5941-DET2:DWF4:SMT2 :Plant increased Campestrol
–주목, 인삼 등 항산화, 항노화, 항암효과 식물의 배양 조성물에 포함됨

Paper Trend
•Resistance for fungal pathogens

-AKT7(AK-Toxin biosynthetic gene 7), encodes a cytochrome P450 monooxygenase and functions to limit AK-toxinproduction. (Takaoka et al., New Phytologist, March 2014)

•Secondary metabolite & antimalarial drug

-Overexpressionof AlleneOxide Cyclase Improves Biosynthesis of Artemisininby increasing expression levels of FPS (farnesyldiphosphate synthase), CYP71A6 (CYP P450 dependent hydroxylase) and DBR2(double bond reductase 2) (Lu et al., PLOSONE, March 2014)

•Bio-Energy

-Exogenouslyapplied 24-epi brassinolide reduces lignificationand alters cell wall carbohydrate biosynthesis in secondary xylem. (Jin et al.,Phytochemistry, March 2014)

•BRs

-Isolationand Characterization of the Brassinosteroid Receptor Gene (GmBRI1) from Glycinemax (Wang et al., Int.J. Mol. Sci. 2014)

•Herbicide tolerance

-Anovel rice cytochrome P450 gene, CYP72A31, confers tolerance to acetolactate synthase-inhibiting herbicides inrice and Arabidopsis. (Saika et al., Plant Physiology, Jan 2014)

-Molecularmechanisms of herbicide-inducible gene expression of tobacco CYP71AH11metabolizing the herbicide chlorotoluron. (Gion et al., Pesticide Biochemistry andPhysiology, Jan 2014)

•Steroid C2 hydroxylase in plant
–Ent-isokaurene C2-hydroxylase (CYP71Z6) in Oriza sativa
–Ent-cassadiene C2-hydroxylase (CYP71Z7) in Oriza sativa

    (2011 Nov, FEBS letters)

•diterpenoid metabolism
–Phytoecdysteroid C2-hydroxylase in spinacia oleracea L. (2009 Dec, Arch Insect BiochemPhysiol.)
–C2-hydroxylase, DDWF1 in Pisum sativum. (Kang et al., 2001 June, Cell)