최희정/ Choi, Hee-Jung
· Lab : 880-6546
· Office : 880-6605
· Lab : 504-306
· Office : 504-331
Structural and biochemical studies by using molecular biology and biochemical techniques as well as X-ray crystallography.
Our target proteins are,
(1) GPCRs (G-protein coupled receptors)
: beta2-adrenergic receptor, Frizzled receptors
Here is the crystal structure of agonist bound active beta2-adrenergic receptor.
(2) proteins involved in crosstalk between cell-cell adhesion system and Hippo signaling pathway
: alpha-catenin, beta-catenin, Merlin, YAP, LATS & MST kinases
Here is the crystal structure of vinculin alpha-catenin peptide complex.