이메일  연구실홈페이지
이름
최희정/  Choi, Hee-Jung
직위 부교수
전공분야 구조생물학
연구실 구조생물학 연구실
전화번호
· Lab : 880-6546
· Office : 880-6605
위치
(동/호)
· Lab : 504-306
· Office : 504-331
주요연구분야 학력/경력 연구논문
연구분야

Structural and biochemical studies by using molecular biology and biochemical techniques as well as X-ray crystallography.

 

Our target proteins are,

 

(1) GPCRs (G-protein coupled receptors)

: beta2-adrenergic receptor, Frizzled receptors

Here is the crystal structure of agonist bound active beta2-adrenergic receptor.

   Choi et al., (2011) Nature, 469, 175-180.

 

(2) proteins involved in crosstalk between cell-cell adhesion system and Hippo signaling pathway

: alpha-catenin, beta-catenin, Merlin, YAP, LATS & MST kinases

Here is the crystal structure of vinculin alpha-catenin peptide complex.

Choi et al., (2012) Proc. Natl. Acad. Sci. USA, 109, 8576-8581.


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