김현아

부교수

김현아 Joy Kim

김현아
연구분야
분자생물학 생물물리학 생화학
Our research goals are to elucidate the molecular mechanisms of membrane protein biogenesis, folding and assembly in eukaryotic cells. Some of the fundamental questions that we attempt to answer are:
1. How does the translocation machinery recognize and sort transmembrane segments into the membrane?
2. Which part(s)/subunit(s) of the translocation machinery mediates recognition and insertion of transmembrane segments?
3. How similar or different the molecular mechanism of membrane protein insertion is in different subcellular organelles?
We use Saccharomyces cerevisiae as a model organism, and yeast genetics, molecular and cell biology techniques.
학력/경력
학력
  • - 1996~2001 박사: Physiology and Biophysics SUNY Stony Brook, USA
  • - 1991~1995 학사: Biochemistry UC Davis, USA
경력
  • - 2015.03.~ 부교수, 서울대학교 생명과학부
  • - 2009.03.~2015.02. 조교수, 서울대학교 생명과학부
  • - 2006.01.~2009.02. Group leader, Center for Biomembrane Research
  • - 2001.12.~2005.12. Postdoctoral fellow, Stockholm University, Sweden
주요논문
  1. Sung-jun Jung, Ji Eun Hani Kim, Johannes H. Reithinger, and Hyun Kim, "The Sec62/Sec63 translocon facilitates the Cout orientation of membrane proteins," J. Cell. Sci., 2014(127), 4270-4278(2014)
  2. Johannes H. Reithinger, Ji Eun Hani Kim, and Hyun Kim, "Sec62 protein mediates membrane insertion and orientation of moderately hydrophobic signal anchor proteins in the endoplasmic reticulum (ER)," J. Biol. Chem., 288(25), 18058-18067(2013)
  3. Kwangjin Park, Salome Calado Botelho, joonki Hong, Marie Osterberg, and Hyun Kim, "Dissecting stop transfer versus conservative sorting pathways for mitochondrial inner membrane proteins in vivo," J. Biol. Chem., 288(3), 1521-1532(2013)
  4. Salomé Calado Botelho, Marie Osterberg, Andreas S Reichert, Koji Yamano, Patrik Björkholm, Toshiya Endo, Gunnar Von Heijne, and Hyun Kim, "TIM23-mediated insertion of transmembrane α-helices into the mitochondrial inner membrane," EMBO J., 30(6), 1003-1011(2011)